Superantigens (SAGs) bind simultaneously to major histocompatibility complex (MHC) and T‐
cell receptor (TCR) molecules, resulting in the massive release of inflammatory cytokines …

Superantigens are unique products of bacteria and viruses which, in combination with class
II major histocompatibility complex molecules, are capable of stimulating a large fraction of T …

“Superantigens” is the term for a group of molecules that have in common an extremely
potent stimulatory activity for T lymphocytes of several species. They stimulate CD4+, CD8+ …

Superantigens are potent immunostimulatory molecules that activate both T cells and
antigen presenting cells. The consequences of superantigen exposure range from induction …

Increasing evidence suggests that superantigens play a role in Immune-mediated diseases.
Superantigens are potent activators of CD4* T cells, causing rapid and massive proliferation …

Superantigens (SAGs) cause a massive T‐cell proliferation by simultaneously binding to
major histocompatibility complex (MHC) class II on antigen‐presenting cells and T‐cell …