Long non-cording RNA XIST promoted cell proliferation and suppressed apoptosis by miR-423-5p/HMGA2 axis in diabetic nephropathy

H Chen, Y Guo, X Cheng - Molecular and Cellular Biochemistry, 2021 - Springer
This research studied the effect of long non-coding RNA X-inactive-specific transcript (XIST)
on DN. The effect of high glucose (HG) on the expression of XIST and miR-423-5p was …

[HTML][HTML] Long non-coding RNA XIST regulates hyperglycemia-associated apoptosis and migration in human retinal pigment epithelial cells

Y Dong, G Wan, G Peng, P Yan, C Qian, F Li - Biomedicine & …, 2020 - Elsevier
Objective Patients with chronic hyperglycemia are at high risk of developing diabetic
retinopathy. In this study, we investigated the functional role of long-noncoding RNA …

Long non‐coding RNA XIST alleviates sepsis‐induced acute kidney injury through inhibiting inflammation and cell apoptosis via regulating miR‐155‐5p/WWC1 axis

L Wang, QM Cao - The Kaohsiung Journal of Medical Sciences, 2022 - Wiley Online Library
Sepsis is characterized by a severe inflammatory response throughout the whole body and
can induce acute kidney injury (AKI). This research aimed to investigate the regulatory …

Long non-coding RNA small nucleolar RNA host gene 5 (SNHG5) regulates renal tubular damage in diabetic nephropathy via targeting MiR-26a-5p

Q Cai, C Wang, L Huang, C Wu, BC Yan… - Hormone and …, 2021 - thieme-connect.com
The study explored the diagnostic value of SNHG5 in diabetic nephropathy (DN) and
investigated the role and mechanism on DN via establishing the in vitro HK2 cell model. This …

A novel mir503hg/miR-497-5p/CCL19 Axis regulates high glucose-induced cell apoptosis, inflammation, and fibrosis in human HK-2 cells

D Zhang, X Chen, D Zheng - Applied biochemistry and biotechnology, 2022 - Springer
Long non-coding RNAs (lncRNAs) play crucial roles in the development of diabetic
nephropathy (DN). Here, we explored the activity and mechanism of MIR503 host gene …

LncRNA XIST protects podocyte from high glucose-induced cell injury in diabetic nephropathy by sponging miR-30 and regulating AVEN expression

B Long, Y Wan, S Zhang, L Lv - Archives of Physiology and …, 2023 - Taylor & Francis
Diabetic nephropathy (DN) is one of the most important complications of diabetes mellitus.
Thus, it is urgent to develop a novel diagnosis or therapeutic strategy that could suspend DN …

[HTML][HTML] MicroRNA 1228 mediates the viability of high glucose-cultured renal tubule cells through targeting thrombospondin 2 and PI3K/AKT signaling pathway

T Mo, Q Fu, X Hu, Y Fu, J Li - Kidney and Blood Pressure Research, 2022 - karger.com
Aim: The present study aimed to elucidate the potential function of microRNA 1228 (miR-
1228) on the high glucose (HG)-damaged human renal proximal tubule cells (HK-2) and the …

[HTML][HTML] Long Non-coding RNA XIST Attenuates Diabetic Peripheral Neuropathy by Inducing Autophagy Through MicroRNA-30d-5p/sirtuin1 Axis

BY Liu, L Li, LW Bai, CS Xu - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
Diabetic peripheral neuropathy (DPN) is a prevalent diabetes mellitus complication and the
primary reason for amputation. Meanwhile, long non-coding RNAs (lncRNAs) are a type of …

[PDF][PDF] Long noncoding RNA XIST enhances cerebral ischemia-reperfusion injury by regulating miR-486-5p and GAB2.

F Xiong, WP Wei, YB Liu, Y Wang… - European Review for …, 2021 - europeanreview.org
OBJECTIVE: LncRNA XIST has been reported to act as diverse function in different human
diseases. Our study is designed to detect the role of lncRNA XIST and the regulatory …

MicroRNA (miR)-590-3p alleviates high-glucose induced renal tubular epithelial cell damage by targeting C-X3-C motif chemokine ligand 1 (CX3CL1) in diabetic …

J Yun, J Ren, Y Liu, L Dai, L Song, X Ma, S Luo… - …, 2022 - Taylor & Francis
We attempted to analyze the clinical value of microRNA (miR)-590-3p in diabetic
nephropathy (DN) patients and its role in high glucose (HG)-induced renal tubular epithelial …