Abstract Interleukin-23/interleukin-23 receptor (IL-23/IL-23R) has been implicated in many
inflammatory diseases. Previous research mainly focused on its ability to induce IL-17 …

Abstract Background Interleukin-23 (IL-23) is required for T helper 17 (Th17) cell responses
and IL-17 production in ischemic stroke. We previously showed that the IL-23/IL-17 axis …

Ischemia–reperfusion frequently occurs in ischemic cerebral vascular disease, during which
the inflammatory signaling plays essential roles. The aim of this study was to discover the …

We previously reported that astrocytes are the main sources of interleukin (IL)‐17A
production that could aggravate neuronal injuries in ischemic stroke. However, the effects of …

Recently, T cell cytokines such as IL-17 and IFN-γ have been shown to play important roles
in the progression of brain injury induced by ischemia. We have shown that IL-23 from …

Interlukin-17 (IL-17) is active in a variety of brain injuries, including ischemia. The objective
of this study was to test the hypothesis that IL-17 potentiates neuronal injury after stroke …

Abstract Background: Interleukin (IL)-17A was reported to be involved in the development of
post-ischemic stroke inflammatory response and functional recovery. However, the IL-17A …

Abstract IL-20, an IL-10 family member, is involved in various inflammatory diseases, such
as psoriasis, rheumatoid arthritis, and atherosclerosis. We investigated whether hypoxia in …

Ischemic brain injury is acute local inflammation, leading to accumulation of pro‐
inflammatory cytokines. Cytokines influence the recruitment of leucocytes and play a key …

Background Interleukin-35 (IL-35), an anti-inflammatory and antioxidant cytokine, plays a
potent immunosuppressive role in various diseases. However, the effects of IL-35 on blood …