Objective: Non-pharmacologic interventions such as ischemic conditioning (IC) markedly
reduce infarct size but it remains unclear whether this protection translates to a significant …

Objective: Ischemic conditioning (IC) limits myocyte necrosis after acute myocardial
ischemia-reperfusion; however, controversy persists regarding its potential to attenuate LV …

We tested the hypothesis that unloading the left ventricle just prior to reperfusion provides
infarct size reduction compared with left ventricular (LV) unloading postreperfusion and …

Objective: Ischemic conditioning (IC) mediated protection against ischemic injury continues
independent of extrinsic cardiac nerve status; however, controversy persists regarding its …

Background We previously reported that pressure overload of the left ventricle reduced
myocardial infarct (MI) size in rabbits. The threshold of pressure overload was investigated …

The modification of reperfusion by Post-Conditioning (PC) following coronary occlusion in
animals significantly reduces myocardial necrosis and improves left-ventricular function …

Background Two types of ischemia, pacing-induced and coronary occlusion–induced, have
different effects on left ventricular diastolic properties. During pacing-induced ischemia, the …

Restoring ischaemic myocardial tissue perfusion is crucial for minimizing infarct size. Acute
mechanical left ventricular (LV) support has been suggested to improve infarct tissue …

New Findings• What is the topic of this review? The gold standards for assessing heart
function in experimental animals are magnetic resonance imaging or high‐frequency …

Background: In a canine preparation of 2 hours of coronary occlusion and 2 hours of
reperfusion, we tested the hypothesis that controlled hydrodynamic conditions (coronary …