STUDY QUESTION Is a protocol that combines in vitro maturation of germinal vesicle-stage
oocytes and their vitrification with freezing of cortical ovarian tissue feasible for use in fertility …

Girls and women suffering from a cancer that requires treatment with gonadotoxic drugs may
experience cessation of reproductive function as a side effect due to obliteration of the …

OBJECTIVE: To determine whether oocyte retrieval and in vitro maturation (IVM) is effective
in girls undergoing fertility preservation before cancer treatment. DESIGN: Cohort study …

Cancer treatments improve the survival rate of children and adolescents; however chemo‐
and radiotherapy result in gonadal damage leading to acute ovarian failure and sterility …

Cryopreservation of embryos, oocytes, or ovarian tissues is the main option for female
fertility preservation. Oocyte cryopreservation has emerged as especially important: the …

Background Oocyte in vitro maturation (IVM) and cryopreservation at the time of routine
ovarian tissue freezing may be offered to cancer patients as an additional option for fertility …

Background Loss of fertility is one of the long‐term adverse effects of high‐dose
chemotherapy or total body irradiation for cancer, even in children. Ovarian tissue …

Ovarian tissue cryopreservation is an option to preserve reproductive potential in patients
who must urgently undergo aggressive chemotherapy and/or radiotherapy or who have …

Purpose Few clinical options for fertility preservation are available to females with cancer,
and data about clinical outcomes is limited. Potential supplementary approaches to fertility …

Children and women of reproductive age are increasingly surviving cancer diagnoses, and
therefore long‐term quality‐of‐life issues are of greater importance at the time of diagnosis …