Astrocytes are the most abundant non-neuronal cells of the central nervous system (CNS)
and are vital for brain homeostasis. This article considers the neuroimmune response, an …

Microglia, as the brain's foremost immune cells, play a pivotal role in maintaining brain
homeostasis through persistent interactions with their environment. In this study, we …

Nicotinic acetylcholine receptor (nAChR) dysregulation in astrocytes is reported in
neurodegenerative disorders. Modulation of nAChRs through agonists confers protection to …

Neurological and neurodegenerative diseases are heterogenous and devastating diseases
with limited therapeutic options and no cures. The broad, long-term goal of this project was …

Astrocytes play crucial roles in the brain and are involved in the neuroinflammatory
response. They become reactive in response to virtually all pathological situations in the …

Glia, including astrocytes, are increasingly at the forefront of neurodegenerative research for
their role in the modulation of neuronal function and survival. Improved understanding of …

Alzheimer's disease (AD) alters astrocytes, but the effect of Aß and Tau pathology is poorly
understood. TRAP-seq translatome analysis of astrocytes in APP/PS1 ß-amyloidopathy and …

Astrocytes play important roles in numerous central nervous system disorders including
autoimmune inflammatory, hypoxic, and degenerative diseases such as Multiple Sclerosis …

Astrocytes can support neuronal survival through a range of secreted signals that protect
against neurotoxicity, oxidative stress, and apoptotic cascades. Thus, analyzing the effects of …

Astrocytes play multiple important roles in brain physiology. In pathological conditions, they
become reactive, which is characterized by morphological changes and upregulation of …