[HTML][HTML] Characterization and functional analysis of three novel liver-expressed antimicrobial peptide 2 (LEAP-2) in Glyptothorax zanaensis

S Cai, P Liu, S Liu, X Cao, J Peng, K Meng, Y Qu - Aquaculture Reports, 2023 - Elsevier
Liver-expressed antimicrobial peptide 2 (LEAP-2) is an important component of innate
immunity, a well-conserved, evolutionarily ancient host defensive mechanism. In this study …

Molecular characterization and antibacterial immunity functional analysis of liver-expressed antimicrobial peptide 2 (LEAP-2) gene in golden pompano (Trachinotus …

Y Lei, R Qiu, Y Shen, Y Zhou, Z Cao, Y Sun - Fish & Shellfish Immunology, 2020 - Elsevier
Abstract Liver-expressed antimicrobial peptide-2 (LEAP-2) is a member of the antimicrobial
peptides family. Research has demonstrated that LEAP-2 contains a number of cations and …

Characterization and functional analysis of liver-expressed antimicrobial peptide-2 (LEAP-2) from golden pompano Trachinotus ovatus (Linnaeus 1758)

B Liu, GD Liu, HY Guo, KC Zhu, L Guo, N Zhang… - Fish & Shellfish …, 2020 - Elsevier
The liver-expressed antimicrobial peptide-2 (LEAP-2) is an important component of the
innate immune defense system and plays an important role in resisting the invasion of …

Characterization and functional analysis of liver-expressed antimicrobial peptide-2 (LEAP-2) in Pelodiscus sinensis

J Fu, W Liu, H Cui, C Song, Y Liu, L Wei - Aquaculture, 2019 - Elsevier
Abstract Liver-expressed antimicrobial peptide-2 (LEAP-2) is a cationic antimicrobial peptide
with two disulfide bonds, and it has been shown to play an important role in the host defence …

Identification of antibacterial activity of liver-expressed antimicrobial peptide 2 (LEAP2) from primitive vertebrate lamprey

Y Wang, Z Wang, Z Gao, Y Luan, Q Li, Y Pang… - Fish & Shellfish …, 2024 - Elsevier
Liver-expressed antimicrobial peptide 2 (LEAP2) is a member of the antimicrobial peptides
family and plays a key role in the innate immune system of organisms. LEAP2 orthologs …

Characterization, evolution and functional analysis of the liver-expressed antimicrobial peptide 2 (LEAP-2) gene in miiuy croaker

T Liu, Y Gao, R Wang, T Xu - Fish & Shellfish Immunology, 2014 - Elsevier
As an evolutionarily older defense strategy, the innate immune is the dominant immune
system and provides a first line of antimicrobial host defense in teleost. Liver-expressed …

Molecular characterization and functional analysis of two distinct liver-expressed antimicrobial peptide 2 (LEAP-2) genes in large yellow croaker (Larimichthys crocea)

HX Li, XJ Lu, CH Li, J Chen - Fish & shellfish immunology, 2014 - Elsevier
Liver-expressed antimicrobial peptide 2 (LEAP-2) plays a vital role in the host innate
immune system. In the present study, two LEAP-2 genes (LcLEAP-2A and LcLEAP-2C) from …

Evolution, expression, and characterisation of liver-expressed antimicrobial peptide genes in ancient chondrostean sturgeons

S Zhang, Q Xu, H Du, Z Qi, Y Li, J Huang, J Di… - Fish & shellfish …, 2018 - Elsevier
Liver-expressed antimicrobial peptide 2 (leap-2) is an evolutionarily ancient molecule that
acts as the key component in vertebrate innate immunity against invading pathogens. Leap …

Molecular characterization, antibacterial and immunoregulatory activities of liver-expressed antimicrobial peptide 2 (LEAP-2) in black rockfish, Sebastes schlegelii

M Zhang, X Yan, C Wang, W Liu, Y Wang, H Jing… - Fish & Shellfish …, 2024 - Elsevier
LEAP2 (liver expression antimicrobial peptide 2), is an antimicrobial peptide widely found in
vertebrates and mainly expressed in liver. LEAP2 plays a vital role in host innate immunity …

Gene structure and expression characteristics of liver-expressed antimicrobial peptide-2 isoforms in mud loach (Misgurnus mizolepis, Cypriniformes)

SY Lee, YK Nam - Fisheries and Aquatic Sciences, 2017 - Springer
Background Liver-expressed antimicrobial peptide-2 (LEAP-2) is an important component of
innate immune system in teleosts. In order to understand isoform-specific involvement and …