An overview of the potential medicinal and pharmaceutical properties of Ru (II)/(III) complexes
A Skoczynska, A Lewinski, M Pokora, P Paneth… - International Journal of …, 2023 - mdpi.com
This review examines the existing knowledge about Ru (II)/(III) ion complexes with a
potential application in medicine or pharmacy, which may offer greater potential in cancer …
potential application in medicine or pharmacy, which may offer greater potential in cancer …
Combination of Ru (II) complexes and light: new frontiers in cancer therapy
The synergistic action of light, oxygen and a photosensitizer (PS) has found applications for
decades in medicine under the name of photodynamic therapy (PDT) for the treatment of …
decades in medicine under the name of photodynamic therapy (PDT) for the treatment of …
Construction of homo and heteronuclear Ru (II), Ir (III) and Re (I) complexes for target specific cancer therapy
More than 10 million death tolls in 2020 were reported as a result of heinous impact of
cancer, making it second most prime cause of death after cardiovascular diseases. In …
cancer, making it second most prime cause of death after cardiovascular diseases. In …
Detailed account on activation mechanisms of ruthenium coordination complexes and their role as antineoplastic agents
M Pal, U Nandi, D Mukherjee - European Journal of Medicinal Chemistry, 2018 - Elsevier
Ruthenium (Ru) complexes are known for their promising anticancer activity presumably
due to octahedral coordination geometry, slow ligand exchange rate, the range of different …
due to octahedral coordination geometry, slow ligand exchange rate, the range of different …
Biological applications of Ru (II) polypyridyl complexes
M Mital, Z Ziora - Coordination Chemistry Reviews, 2018 - Elsevier
Ru (II) polypyridyl complexes are of great interest for their unique biological, photophysical,
optical, catalytic and electronic properties. This class of complexes demonstrates a number …
optical, catalytic and electronic properties. This class of complexes demonstrates a number …
Study of ruthenium (II) complexes with anticancer drugs as ligands. Design of metal-based phototherapeutic agents
R Cini, G Tamasi, S Defazio, M Corsini… - Inorganic …, 2003 - ACS Publications
The reaction of trans-[RuCl2 (PPh3) 3](Ph= C6H5) with 2-thio-1, 3-pyrimidine (HTPYM) and
6-thiopurines (TPs) produced mainly crystalline solids that consist of cis, cis, trans-[Ru …
6-thiopurines (TPs) produced mainly crystalline solids that consist of cis, cis, trans-[Ru …
Systematic investigation of the antiproliferative activity of a series of ruthenium terpyridine complexes
Due to acquired resistance or limitations of the currently approved drugs against cancer,
there is an urgent need for the development of new classes of compounds. Among others …
there is an urgent need for the development of new classes of compounds. Among others …
Design of a tris-heteroleptic Ru (II) complex with red-light excitation and remarkably improved photobiological activity
S Li, J Zhao, X Wang, G Xu, S Gou, Q Zhao - Inorganic Chemistry, 2020 - ACS Publications
Ru (II)-polypyridyl complexes are of increasing interest in photodynamic therapy (PDT) due
to their easily tunable photophysical and photochemical properties. However, short …
to their easily tunable photophysical and photochemical properties. However, short …
Recent advances in ruthenium (II) and iridium (III) complexes containing nanosystems for cancer treatment and bioimaging
J Shen, TW Rees, L Ji, H Chao - Coordination chemistry reviews, 2021 - Elsevier
Ruthenium (II) and iridium (III) coordination compounds display excellent structural,
photophysical, and biological properties which make them highly promising as anticancer …
photophysical, and biological properties which make them highly promising as anticancer …
New ruthenium polypyridyl complexes functionalized with fluorine atom or furan: Synthesis, DNA-binding, cytotoxicity and antitumor mechanism studies
GB Jiang, WY Zhang, M He, YY Gu, L Bai… - … Acta Part A: Molecular …, 2020 - Elsevier
Two novel ruthenium (II) polypyridyl complexes, namely,[Ru (dmp) 2 (CAPIP)](ClO 4) 2 (Ru
(II)-1) and [Ru (dmp) 2 (CFPIP)](ClO 4) 2 (Ru (II)-2), which respectively contain (E)-2-(2 …
(II)-1) and [Ru (dmp) 2 (CFPIP)](ClO 4) 2 (Ru (II)-2), which respectively contain (E)-2-(2 …