The ability to accurately detect early ovarian cancer and subsequently monitor treatment
response is essential to improving survival for patients with ovarian malignancies. Several …

OBJECTIVE: Ovarian cancer has the highest mortality of all the gynecologic malignancies
with most patients diagnosed at late stages. Serum CA-125 is elevated in only half of …

Ovarian cancer (OC) is characterized by silent progression and late-stage diagnosis. It is
critical to detect and accurately diagnose the disease early to improve survival rates. Tumor …

Ovarian cancer (OC) is the most lethal gynaecologic malignancy, attributed to its insidious
growth, non-specific symptoms and late presentation. Unfortunately, current screening …

Epithelial ovarian cancer (EOC) is the deadliest gynaecological malignancy and the eighth
most prevalent cancer in women, with an abysmal mortality rate of two million worldwide …

Cancer Antigen 125 (CA125) and Human Epididymis Protein 4 (HE4) are the most studied
ovarian tumor markers. Their diagnostic performance for identification of ovarian cancer are …

Background: Ovarian cancer has a low incidence, but high mortality due to a habitual
diagnosis in advanced cancer stages. Currently, used biomarkers have good sensitivity, but …

Purpose To investigate the diagnostic values of human epididymis protein 4 (HE4),
carbohydrate antigen 125 (CA125), carbohydrate antigen 19-9 (CA19-9), and …

Abstract Background: Updated National Academy of Clinical Biochemistry (NACB)
Laboratory Medicine Practice Guidelines for the use of tumor markers in the clinic have been …

The 125th attempt to develop a monoclonal antibody against ovarian cancer in a laboratory
at the Dana-Farber Cancer Institute (Boston, MA) led to the discovery of one of the most …