Influence of genotype and haplotype of MDR1 (C3435T, G2677A/T, C1236T) on the incidence of breast cancer-a case-control study in Jordan

MA Ali, AMF Yousef, NN El-Madany… - Asian pacific journal …, 2016 - journal.waocp.org
Background: Breast cancer is the leading cause of cancer death among women and the
second in humans worldwide. Many published studies have suggested an association …

Association of C3435T Single-Nucleotide Polymorphism of MDR1 Gene with Breast Cancer in an Iranian Population

F Tatari, R Salek, F Mosaffa, A Khedri… - DNA and cell …, 2009 - liebertpub.com
The human multidrug resistance gene 1 (MDR1) encodes a plasma membrane, P-
glycoprotein (Pgp), which functions as the transmembrane efflux pump for various …

Association between MDR1 C3435T polymorphism and risk of breast cancer

Z Wang, T Wang, J Bian - Gene, 2013 - Elsevier
Abstract The C3435T (rs1045642) polymorphism, located in multi-drug resistance gene 1
(MDR1), has demonstrated its role in decreasing the P-gp activity level which is related to …

Investigation on MDR1 gene polymorphisms and its relationship with breast cancer risk factors in Chinese women

Y Fang, Q Zhao, G Ma, Y Han, N Lou - Medical Oncology, 2013 - Springer
The human multidrug resistance 1 gene (MDR1) is an important candidate gene influencing
the susceptibility to various diseases, including breast cancer. The object of this study was to …

A polymorphism C3435T of the MDR-1 gene associated with smoking or high body mass index increases the risk of sporadic breast cancer in women

P Zubor, Z Lasabova, J Hatok… - Oncology …, 2007 - spandidos-publications.com
The human multidrug resistance gene 1 (MDR-1) encodes a plasma membrane P-
glycoprotein (P-gp) that functions as the transmembrane efflux pump for various structurally …

[HTML][HTML] C3435T polymorphism in the MDR1 gene and breast cancer risk in northeastern Mexico

G Jaramillo-Rangel, M Ortega-Martínez… - … Journal of Clinical …, 2018 - ncbi.nlm.nih.gov
The multidrug resistance gene 1 (MDR1) encodes a membrane-bound phosphoglycoprotein
(P-gp). It functions as a transmembrane efflux pump for various structurally unrelated …

The association between genetic variant of MDR1 gene and breast cancer risk factors in Chinese women

L Gao, Y Yang, S Song, H Hong, X Zhao, D Li - International …, 2013 - Elsevier
Previous studies indicated that the human multidrug resistance 1 gene (MDR1) is an
important candidate gene influencing the susceptibility to breast cancer. The purpose of this …

MDR1 C3435T polymorphism in patients with breast cancer

S Turgut, A Yaren, R Kursunluoglu, G Turgut - Archives of medical research, 2007 - Elsevier
BACKGROUND: The human multidrug-resistant gene (MDR1) encodes P-glycoprotein
(Pgp), a membrane-bound efflux transporter conferring resistance to a number of natural …

[HTML][HTML] Association of gastric cancer incidence with MDR1 gene polymorphism in an ethnic Iranian population

Z Sabahi, R Salek, RE Heravi, F Mosaffa… - Indian journal of …, 2010 - journals.lww.com
BACKGROUND: The allele frequency of the multidrug resistance 1 (MDR1) gene C3435T
polymorphism differs with different ethnic populations, such as Asian, African, and …

[HTML][HTML] Haplotype Analysis of MDR1 and risk for cervical cancer in northeastern Thailand

S Phuthong, W Settheetham-Ishida… - Asian Pacific journal …, 2017 - ncbi.nlm.nih.gov
Objective: The aim of this study was to investigate the association between genotype and
haplotype of MDR1 (C1236T, G2677T/A and C3435T) and the risk for cervical cancer in …