[HTML][HTML] Different dose regimens of a SARS-CoV-2 recombinant spike protein vaccine (NVX-CoV2373) in younger and older adults: A phase 2 randomized placebo …

N Formica, R Mallory, G Albert, M Robinson… - PLoS …, 2021 - journals.plos.org
Background NVX-CoV2373 is a recombinant severe acute respiratory coronavirus 2 (rSARS-
CoV-2) nanoparticle vaccine composed of trimeric full-length SARS-CoV-2 spike …

Safety and efficacy of NVX-CoV2373 Covid-19 vaccine

PT Heath, EP Galiza, DN Baxter, M Boffito… - … England Journal of …, 2021 - Mass Medical Soc
Background Early clinical data from studies of the NVX-CoV2373 vaccine (Novavax), a
recombinant nanoparticle vaccine against severe acute respiratory syndrome coronavirus 2 …

[HTML][HTML] Phase 1–2 trial of a SARS-CoV-2 recombinant spike protein nanoparticle vaccine

C Keech, G Albert, I Cho, A Robertson… - New england journal …, 2020 - Mass Medical Soc
Background NVX-CoV2373 is a recombinant severe acute respiratory syndrome
coronavirus 2 (rSARS-CoV-2) nanoparticle vaccine composed of trimeric full-length SARS …

[HTML][HTML] Efficacy and safety of NVX-CoV2373 in adults in the United States and Mexico

LM Dunkle, KL Kotloff, CL Gay, G Áñez… - … England Journal of …, 2022 - Mass Medical Soc
Background NVX-CoV2373 is an adjuvanted, recombinant spike protein nanoparticle
vaccine that was shown to have clinical efficacy for the prevention of coronavirus disease …

Safety and immunogenicity following a homologous booster dose of a SARS-CoV-2 recombinant spike protein vaccine (NVX-CoV2373): a secondary analysis of a …

RM Mallory, N Formica, S Pfeiffer… - The Lancet Infectious …, 2022 - thelancet.com
Summary Background Emerging SARS-CoV-2 variants and evidence of waning vaccine
efficacy present substantial obstacles towards controlling the COVID-19 pandemic. Booster …

Efficacy of NVX-CoV2373 Covid-19 vaccine against the B. 1.351 variant

V Shinde, S Bhikha, Z Hoosain, M Archary… - … England Journal of …, 2021 - Mass Medical Soc
Background The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) variants threatens progress toward control of the coronavirus disease 2019 (Covid …

[HTML][HTML] Immunogenicity and safety of a SARS-CoV-2 recombinant spike protein nanoparticle vaccine in people living with and without HIV-1 infection: a randomised …

SA Madhi, D Moodley, S Hanley, M Archary… - The Lancet …, 2022 - thelancet.com
Background There is a paucity of data on COVID-19 vaccines in people living with HIV-1,
who could be at increased risk of severe illness and death from COVID-19. We evaluated …

Safety and efficacy of the NVX-CoV2373 coronavirus disease 2019 vaccine at completion of the placebo-controlled phase of a randomized controlled trial

PT Heath, EP Galiza, DN Baxter… - Clinical Infectious …, 2023 - academic.oup.com
Background The recombinant protein-based vaccine, NVX-CoV2373, demonstrated 89.7%
efficacy against coronavirus disease 2019 (COVID-19) in a phase 3, randomized, observer …

[HTML][HTML] A preliminary report of a randomized controlled phase 2 trial of the safety and immunogenicity of mRNA-1273 SARS-CoV-2 vaccine

L Chu, R McPhee, W Huang, H Bennett, R Pajon… - Vaccine, 2021 - Elsevier
Background Vaccines are urgently needed to prevent the global spread of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). We assessed the safety and …

Safety, immunogenicity, and efficacy of the NVX-CoV2373 COVID-19 vaccine in adolescents: a randomized clinical trial

G Áñez, LM Dunkle, CL Gay, KL Kotloff… - JAMA network …, 2023 - jamanetwork.com
Importance Greater than 20% of cases and 0.4% of deaths from COVID-19 occur in children.
Following demonstration of the safety and efficacy of the adjuvanted, recombinant spike …