Mechanisms regulating energy metabolism by adiponectin in obesity and diabetes

X Fang, G Sweeney - 2006 - portlandpress.com
Nutritional control of molecular events has become of great interest given the increased
incidence of diet-induced obesity, and consequently Type 2 (non-insulin-dependent) …

Evidence for the neuronal expression and secretion of adiponectin

A Abgrall, G Poizat, M Prevost, L Riffault… - Cells, 2022 - mdpi.com
Peripheral adiponectin acts on the hypothalamus to inhibit energy expenditure and increase
food intake through its receptors AdipoR1 and adipoR2. The hypothalamic expression of …

[HTML][HTML] Adiponectin and lipid metabolism in skeletal muscle

B Lee, J Shao - Acta Pharmaceutica Sinica B, 2012 - Elsevier
White adipose tissue (WAT) is a key energy depot in humans and most animals.
Traditionally, it is believed that WAT passively accumulates triglycerides or releases fatty …

Opposing effects of adiponectin receptors 1 and 2 on energy metabolism

M Bjursell, A Ahnmark, M Bohlooly-Y… - Diabetes, 2007 - Am Diabetes Assoc
The adipocyte-derived hormone adiponectin regulates glucose and lipid metabolism and
influences the risk for developing obesity, type 2 diabetes, and cardiovascular disease …

Adiponectin: a key player in obesity related disorders

Y Matsuzawa - Current pharmaceutical design, 2010 - ingentaconnect.com
Recent studies revealed that adipose tissue is not only an energy storing organ, but is a kind
of endocrine organ which secretes a variety of bioactive substances, so-called adipokines or …

Lifestyle factors increasing adiponectin synthesis and secretion

JM Tishinsky, DJ Dyck, LE Robinson - Vitamins & Hormones, 2012 - Elsevier
Adiponectin is an anti-inflammatory adipokine released from adipose tissue that is known to
exert insulin-sensitizing effects in skeletal muscle and liver. Given that the secretion of …

Central adiponectin acutely improves glucose tolerance in male mice

CE Koch, C Lowe, K Legler, J Benzler… - …, 2014 - academic.oup.com
Adiponectin, an adipocyte-derived hormone, regulates glucose and lipid metabolism. It is
also antiinflammatory. During obesity, adiponectin levels and sensitivity are reduced …

Role of adiponectin system in insulin resistance

C Caselli - Molecular genetics and metabolism, 2014 - Elsevier
The knowledge of the pathogenesis of obesity and its metabolic sequelae has significantly
advanced over the last few decades and adipose tissue is now considered a link between …

Expression of adiponectin and adiponectin receptors in human pituitary gland and brain

A Psilopanagioti, H Papadaki, EF Kranioti… - …, 2009 - karger.com
Background/Aims: Adiponectin and its receptors, AdipoR1 and AdipoR2, constitute integral
components of energy homeostatic mechanism in peripheral tissues. Recent studies have …

Physiological and pathophysiological roles of adiponectin and adiponectin receptors in the integrated regulation of metabolic and cardiovascular diseases

T Yamauchi, T Kadowaki - International journal of obesity, 2008 - nature.com
Adiponectin and adiponectin receptors (AdipoRs) have been found to play significant roles
in the etiology of obesity-related chronic disease. Their discovery has been a long and …