Intracellular invasion is an advantageous mechanism used by pathogens to evade host
defense and antimicrobial therapy. In patients, the intracellular microbial lifestyle can lead to …

Pseudomonas aeruginosa is one of the main microbial species colonizing the lungs of cystic
fibrosis patients and is responsible for the decline in respiratory function. Despite the hostile …

Chronic lung infections are associated with increased morbidity and mortality for individuals
with underlying respiratory conditions such as cystic fibrosis (CF) and chronic obstructive …

While several environmental factors contribute to the evolutionary diversification of the
pathogenic bacterium Pseudomonas aeruginosa during cystic fibrosis lung infections …

Pseudomonas aeruginosa is the leading pathogen of chronic cystic fibrosis (CF) lung
infection. Life-long persistance of P. aeruginosa in the CF lung requires a sophisticated …

Pseudomonas aeruginosa is a versatile opportunistic pathogen causing a wide variety of
hospital-acquired acute infections in immunocompromised patients as well as chronic …

The opportunistic pathogen Pseudomonas aeruginosa is able to thrive in diverse ecological
niches and to cause serious human infection. P. aeruginosa environmental strains are …

The long-term persistance of P. aeruginosa in the cystic fibrosis (CF) lung is characterized
by the selection of a variety of genotypes and phenotypes that typically descend from one …

Pseudomonas aeruginosa populations undergo a characteristic evolutionary adaptation
during chronic infection of the cystic fibrosis (CF) lung, including reduced production of …

Pseudomonas aeruginosa is the most prevalent pathogen of cystic fibrosis (CF) lung
disease. Its long persistence in CF airways is associated with sophisticated mechanisms of …