Despite extensive research into understanding synaptic mechanisms of striatal plasticity, the
functional role played by astrocytes in this region remains to be fully elucidated. It was …

Astrocytes regulate multiple aspects of neuronal and synaptic function from development
through to adulthood. Instead of addressing each function independently, this review …

▪ Abstract Astrocytes, a sub-type of glia in the central nervous system, are dynamic signaling
elements that integrate neuronal inputs, exhibit calcium excitability, and can modulate …

Close structural and functional interactions of astrocytes with synapses play an important
role in brain function. The repertoire of ways in which astrocytes can regulate synaptic …

Astrocytes can respond to neurotransmitters released at the synapse by generating
elevations in intracellular Ca2+ concentration ([Ca2+] i) and releasing glutamate that signals …

Although neurons are essential for brain function, an emerging alternative view holds that
astrocytes, the dominant glial cell type, coordinate synaptic networks. Through the release of …

Astrocytes, classically considered as supportive cells for neurons without a direct role in
brain information processing, are emerging as relevant elements in brain physiology …

A major breakthrough in neuroscience has been the realization in the last decades that the
dogmatic view of astroglial cells as being merely fostering and buffering elements of the …

In the central nervous system (CNS), astrocytes form an intimately connected network with
neurons and their processes often closely enwrap synapses. The critical role of these cells …

The physiological functions of astrocytes within neural circuits remain incompletely
understood. There has been progress in this regard from recent work on striatal astrocytes …