Precision medicine is a tailored approach to health, incorporating an individual's genetic
make-up, environment and lifestyle, and is a new frontier offering much promise for disease …

The knowledge gained from patients' genome sequences will increasingly help inform their
diagnoses and clinical management. For the health system, the aims of genomic medicine …

Recent technological advances have enabled assembly of a wide range of data about an
individual's genetic and biochemical makeup, as formed by their genes, environment and …

The 100,000 Genomes Project has been the first genomics initiative in the world to recruit
patients through routine care and offer treatment through routine channels. As recruitment to …

Clinical practice is shifting towards an era of precision medicine where molecular insights
enable treatment to be personalised to the unique genomic profile of a patient's tumour. 1–3 …

Over the past 3 decades a series of discoveries in the specialty of ophthalmology have been
central to furthering the understanding of genetic disease. However, currently ophthalmic …

Many disorders we encounter in clinical medicine have a genomic basis, from rare “single
gene” disorders such as cystic fibrosis, to complex, polygenic disorders such as ischaemic …

As the UK exits the European Union, there is a pressing need for the UK to invest in
regulatory science and innovation if it is to be globally competitive and internationally …

Virtually all medical specialties are impacted by genetic disease. Enhanced understanding
of the role of genetics in human disease, coupled with rapid advancement in sequencing …

In light of the increasing momentum towards personalised medicine and healthcare, driven
by genomic science and a spectrum of technological and information tools [1], we discuss …