MicroRNAs and drug resistance of breast cancer: basic evidence and clinical applications

W Tian, J Chen, H He, Y Deng - Clinical and Translational Oncology, 2013 - Springer
Breast cancer is the most common malignancy and leading cause of cancer mortality in
women. Drug resistance is a major obstacle in systemic therapy of breast cancer, which …

The role of microRNAs in the chemoresistance of breast cancer

J Wang, M Yang, Y Li, B Han - Drug development research, 2015 - Wiley Online Library
ABSTRACT Preclinical Research Breast cancer is the most prevalent malignancy in women
with more than 1.3 million new cases every year worldwide. Chemotherapy is a critical …

Breast cancer: miRNAs monitoring chemoresistance and systemic therapy

S Singh, H Saini, A Sharma, S Gupta… - Frontiers in …, 2023 - frontiersin.org
With a high mortality rate that accounts for millions of cancer-related deaths each year,
breast cancer is the second most common malignancy in women. Chemotherapy has …

Cross-roads to drug resistance and metastasis in breast cancer: miRNAs regulatory function and biomarker capability

N Naser Al Deen, F Nassar, R Nasr… - Breast Cancer Metastasis …, 2019 - Springer
Breast cancer and specifically metastatic breast cancer (mBC) constitutes a major health
burden worldwide with the highest number of cancer-related mortality among women across …

[HTML][HTML] Emerging role of microRNAs in drug-resistant breast cancer

S Majumder, ST Jacob - Gene expression, 2011 - ncbi.nlm.nih.gov
Intrinsic or acquired resistance to commonly used therapeutic agents is a major challenge in
treating cancer patients. Decades of research have unraveled several unique and common …

MicroRNAs in breast cancer: one More Turn in Regulation

PE Asensio, ET Martin, BP Merlo… - Current drug …, 2016 - ingentaconnect.com
MicroRNAs (miRNAs) are small non-coding RNA molecules that critically regulate the
expression of genes. MiRNAs are involved in physiological cellular processes; however …

The role of microRNA in resistance to breast cancer therapy

NM Robertson, MV Yigit - Wiley Interdisciplinary Reviews: RNA, 2014 - Wiley Online Library
MicroRNAs (miRNAs) are small noncoding RNA molecules with big implications in cancer.
The abnormal expression of specific miRNAs has been linked to development of many …

Role of microRNA deregulation in breast cancer cell chemoresistance and stemness

TA Tekiner, H Basaga - Current medicinal chemistry, 2013 - ingentaconnect.com
Studies with breast cancer cells, showed that microRNAs (miRNAs) act as regulators of
signaling pathways playing a key role in tumor progression and being targeted in …

MicroRNA-mediated drug resistance in breast cancer

KR Kutanzi, OV Yurchenko, FA Beland… - Clinical …, 2011 - Springer
Chemoresistance is one of the major hurdles to overcome for the successful treatment of
breast cancer. At present, there are several mechanisms proposed to explain drug …

The impact of microRNAs on the resistance of breast cancer subtypes to chemotherapy

A Ebrahimi, PB Shahrebabaki, H Fouladi… - … -Research and Practice, 2023 - Elsevier
Breast cancer (BC) formation is primarily influenced by genetics, epigenetics and
environmental factors. Aberrant Genetics and epigenetics leads to a condition known as …