Bone defect repair at load-bearing sites is a challenging clinical problem for orthopedists.
Defect reconstruction with implants is the most common treatment; however, it requires the …

Bone regeneration is a highly synchronized process that requires multiple biochemical,
bioelectrical, mechanical, and other physiological cues. The restoration and delivery of …

Porous titanium scaffolds can provide sufficient mechanical support and bone growth space
for large segmental bone defect repair. However, they fail to restore the physiological …

The prevalence of large bone defects is still a major problem in surgical clinics. It is, thus, not
a surprise that bone-related research, especially in the field of bone tissue engineering, is a …

For large segmental bone defects, porous titanium scaffolds have some advantages,
however, they lack electrical activity which hinders their further use. In this study, a barium …

Abstract The use of Ti6Al4V in bone engineering is limited, due to the biological inertia of the
surface. In this study, a porous Ti6Al4V scaffold with mechanical properties similar to …

Piezoelectric effect of polyvinylidene fluoride (PVDF) plays a crucial role in restoring the
endogenous electrical microenvironment of bone tissue, whereas more β phase in PVDF …

Background Titanium implants are widely used in orthopedic and dental for more than 30
years. Its stable physicochemical properties and mechanical strength are indeed …

Bone regeneration is a well-orchestrated process involving electrical, biochemical, and
mechanical multiple physiological cues. Electrical signals play a vital role in the process of …

There is an evident advantage in personalized customization of orthopedic implants by 3D-
printed titanium (Ti) and its alloys. However, 3D-printed Ti alloys have a rough surface …