Postnatal developmental expression of apelin receptor proteins and its role in juvenile mice testis

M Das, G Gurusubramanian, VK Roy - The Journal of Steroid Biochemistry …, 2022 - Elsevier
The expression of apelin system has been shown in the adult testis of rat and mice. It has
also been emphasized that regulation of testicular activity in early stages is important to …

Expression and localization of apelin and its receptor in the testes of diabetic mice and its possible role in steroidogenesis

M Das, L Annie, KV Derkach, AO Shpakov… - Cytokine, 2021 - Elsevier
Type 1 diabetes mellitus (T1DM) is a metabolic disorder with severe hyperglycemia, one of
the complications of which is testicular dysfunctions, androgen deficiency and decreased …

Postnatal developmental expression and localization of apelin and apelin receptor protein in the ovary and uterus of mice

B Anima, G Guruswami, VK Roy - Molecular Reproduction and …, 2023 - Wiley Online Library
Postnatal ovarian and uterine development is crucial to accomplished female fertility. Thus,
the investigations of factors that present in pre‐pubertal stages are important as it might be …

Apelin receptor antagonist (ML221) treatment has a stimulatory effect on the testicular proliferation, antioxidants system and steroidogenesis in adult mice

M Das, G Gurusubramanian, VK Roy - Neuropeptides, 2023 - Elsevier
The expression of apelin and its receptor (APJ) has been shown in the hypothalamus-
pituitary-testicular axis. It has also been suggested apelin and APJ are neuropeptide factors …

[HTML][HTML] Presence and localization of apelin and its cognate receptor in canine testes using immunohistochemical and RT-PCR techniques

A Troisi, C Dall'Aglio, M Maranesi, R Orlandi… - Veterinary Research …, 2023 - Springer
Apelin, a member of the adipokine family, is a novel endogenous peptide which regulates
the male reproductive system of mammals by interacting with a specific receptor. Recent …

Expression of apelin and apelin receptor (APJ) in porcine ovarian follicles and in vitro effect of apelin on steroidogenesis and proliferation through APJ activation and …

A Rak, E Drwal, C Rame, K Knapczyk-Stwora… - Theriogenology, 2017 - Elsevier
Apelin was thought to be an adipocyte-specific hormone, but recent studies indicate a link
between apelin and female reproductive function. Using real-time PCR, immunoblotting …

Apelin in reproductive physiology and pathology of different species: a critical review

P Kurowska, A Barbe, M Różycka… - International journal …, 2018 - Wiley Online Library
Apelin has been isolated from the bovine stomach extracts as an endogenous ligand of the
previously orphan receptor APJ. Expression of the apelinergic system (apelin and APJ) was …

Possible role of apelin on the ovarian steroidogenesis and uterine apoptosis of infantile mice: An in vitro study

B Anima, G Gurusubramanian, VK Roy - The Journal of Steroid …, 2024 - Elsevier
The expression of adipokines is well-known in the ovary and uterus. Recently we have
shown that apelin and its receptor, APJ are developmentally regulated in the ovary and …

Apelin (APLN) and apelin receptor (APLNR) in human ovary: expression, signaling, and regulation of steroidogenesis in primary human luteinized granulosa cells

J Roche, C Ramé, M Reverchon… - Biology of …, 2016 - academic.oup.com
Apelin (APLN) is a recently discovered adipokine involved in the regulation of various
metabolic functions. Its receptor, APLNR, is expressed in reproductive tissues, however, its …

[HTML][HTML] Molecular properties of apelin: tissue distribution and receptor binding

Y Kawamata, Y Habata, S Fukusumi, M Hosoya… - … et Biophysica Acta (BBA …, 2001 - Elsevier
We analyzed the tissue distribution of apelin mRNA in rats by a quantitative reverse
transcription-polymerase chain reaction and that of immunoreactive apelin (ir-apelin) by an …