Simple Summary Glioblastoma multiforme is an aggressive grade IV lethal brain tumour with
a median survival of 14 months. Despite surgery to remove the tumour, and subsequent …

Malignant gliomas are the most common primary central nervous system tumors and their
prognosis is very poor. In recent years, ion channels have been demonstrated to play …

Ion channels provide the basis for the nervous system's intrinsic electrical activity. Neuronal
excitability is a characteristic property of neurons and is critical for all functions of the …

Malignant gliomas are the most common primary brain tumors and have poor clinical
prognosis, despite multimodal therapeutic strategies. In recent years, ion channels have …

Glioblastoma is the most common primary brain tumor with the most dismal prognosis. It is
characterized by extensive invasion, migration, and angiogenesis. Median survival is only …

Ion channels are expressed in many cancers and contribute to disease progression. A
number of ion channels are well established as clinical targets for a range of (noncancer) …

Ion channels, specifically those controlling the flux of potassium across cell membranes,
have recently been shown to exhibit an important role in the pathophysiology of glioma, the …

Mammalian cells express a large number of structurally distinct ion channels on the cell
surface and also in the membranes of intracellular organelles. They can selectively …

Simple Summary Glioblastoma is a rapidly progressing brain cancer that is very difficult to
treat. Given that many aspects of cell and tissue behavior are controlled by electric signaling …

Plasma membrane (PM) ion channels contribute to virtually all basic cellular processes and
are also involved in the malignant phenotype of cancer cells. Here, we review the role of ion …