Plasma biomarkers identify older adults at risk of Alzheimer's disease and related dementias in a real‐world population‐based cohort

PCL Ferreira, Y Zhang, B Snitz… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction Plasma biomarkers—cost effective, non‐invasive indicators of Alzheimer's
disease (AD) and related disorders (ADRD)—have largely been studied in clinical research …

LDL cholesterol and uridine levels in blood are potential nutritional biomarkers of AD progression: The NUDAD project: Biomarkers (non‐neuroimaging)/Novel …

FA de Leeuw, BM Tijms, AS Doorduijn… - Alzheimer's & …, 2020 - Wiley Online Library
Background Suboptimal nutritional status is considered a modifiable risk factor for
Alzheimer's disease (AD). Identification of nutritional biomarker levels that are related to …

Effects of a six-month multi-ingredient nutrition supplement intervention of omega-3 polyunsaturated fatty acids, vitamin D, resveratrol, and whey protein on cognitive …

C Moran, A Scotto di Palumbo, J Bramham… - The journal of …, 2018 - Springer
Objectives To investigate the impact of a six-month multi-ingredient nutrition supplement
intervention (Smartfish®), containing omega-3 polyunsaturated fatty acids (PUFAs), vitamin …

Relationship between baseline plasma p‐tau181 and longitudinal changes in cognition and structural brain measures in a cohort of cognitively unimpaired older …

MV Pais, CL Kuo, BM Ances… - Alzheimer's & …, 2023 - Wiley Online Library
INTRODUCTION Preclinical Alzheimer's disease (AD) affects a significant proportion of
cognitively unimpaired (CU) older adults. Currently, blood‐based biomarkers detect very …

[引用][C] P1‐278: The efficacy of a medical food (Souvenaid®) in Alzheimer's disease: Results from the first trial and design of future trials

P Scheltens, FRJ Verhey… - Alzheimer's & …, 2009 - Wiley Online Library
Background Many epidemiological studies indicate a clear link between nutrition and
Alzheimer's Disease (AD). Several nutrient deficiencies have been shown to be risk factors …

Plasma pTau181 and pTau217 predict asymptomatic amyloid accumulation equally well as amyloid-PET

S De Meyer, JM Schaeverbeke, ES Luckett… - Brain …, 2024 - academic.oup.com
The dynamic phase of preclinical Alzheimer's disease, as characterised by accumulating
cortical amyloid-β (Aβ), is a window of opportunity for Aβ lowering therapies to have greater …

Eicosapentaenoic acid is associated with decreased incidence of Alzheimer's dementia in the oldest old

D Melo van Lent, S Egert, S Wolfsgruber, L Kleineidam… - Nutrients, 2021 - mdpi.com
Background. Omega-3 (n-3) and omega-6 (n-6) polyunsaturated fatty acids (PUFAs) may
have different effects on cognitive health due to their anti-or pro-inflammatory properties …

Diet and biomarkers of Alzheimer's disease: a systematic review and meta-analysis

E Hill, AM Goodwill, A Gorelik, C Szoeke - Neurobiology of aging, 2019 - Elsevier
Alzheimer's disease (AD) risk increases with age and lacks efficacious pharmacological
options. Summaries of the existing evidence reveal an association between Mediterranean …

Associations between nutritional deficits and physical performance in community-dwelling older adults

WH Lu, KV Giudici, Y Rolland, S Guyonnet… - Frontiers in …, 2021 - frontiersin.org
Background: Whether multiple nutritional deficiencies have a synergic effect on mobility loss
remains unknown. This study aims to evaluate associations between multi-nutritional deficits …

Precision Nutrition for Alzheimer's Prevention in ApoE4 Carriers

NG Norwitz, N Saif, IE Ariza, RS Isaacson - Nutrients, 2021 - mdpi.com
The ApoE4 allele is the most well-studied genetic risk factor for Alzheimer's disease, a
condition that is increasing in prevalence and remains without a cure. Precision nutrition …