New insight into the role of extracellular vesicles in kidney disease

LL Lv, Y Feng, TT Tang, BC Liu - Journal of cellular and …, 2019 - Wiley Online Library
Extracellular vesicles (EVs) are released to maintain cellular homeostasis as well as to
mediate cell communication by spreading protective or injury signals to neighbour or remote …

[HTML][HTML] Novel aspects of extracellular vesicles in the regulation of renal physiological and pathophysiological processes

JP Rigalli, ER Barros, V Sommers… - Frontiers in Cell and …, 2020 - frontiersin.org
Extracellular vesicles (EV) are nanosized particles released by a large variety of cells. They
carry molecules such as proteins, RNA and lipids. While urinary EVs have been longer …

[HTML][HTML] Extracellular vesicles in renal pathophysiology

MAC Pomatto, C Gai, B Bussolati… - Frontiers in molecular …, 2017 - frontiersin.org
Extracellular vesicles are a heterogeneous population of microparticles released by virtually
all living cells which have been recently widely investigated in different biological fields …

[HTML][HTML] Urinary extracellular vesicles: uncovering the basis of the pathological processes in kidney-related diseases

G Cricrì, L Bellucci, G Montini, F Collino - International Journal of …, 2021 - mdpi.com
Intercellular communication governs multicellular interactions in complex organisms. A
variety of mechanisms exist through which cells can communicate, eg, cell-cell contact, the …

Therapeutic application of extracellular vesicles in kidney disease: promises and challenges

LL Lv, WJ Wu, Y Feng, ZL Li, TT Tang… - Journal of cellular and …, 2018 - Wiley Online Library
Extracellular vesicles (EV s) are nanosized, membrane‐bound vesicles released from
different cells. Recent studies have revealed that EV s may participate in renal tissue …

Urinary extracellular vesicles and the kidney: biomarkers and beyond

M Salih, R Zietse, EJ Hoorn - American Journal of …, 2014 - journals.physiology.org
Extracellular vesicles have been isolated in various body fluids, including urine. The cargo
of urinary extracellular vesicles (uEVs) is composed of proteins and nucleic acids reflecting …

Extracellular vesicles in diagnosis and therapy of kidney diseases

W Zhang, X Zhou, H Zhang, Q Yao… - American Journal of …, 2016 - journals.physiology.org
Extracellular vesicles (EV) are endogenously produced, membrane-bound vesicles that
contain various molecules. Depending on their size and origins, EVs are classified into …

[HTML][HTML] Urinary extracellular vesicles as biomarkers of kidney disease: from diagnostics to therapeutics

IO Sun, LO Lerman - Diagnostics, 2020 - mdpi.com
Cell-derived extracellular vesicles (EVs) can be isolated from various body fluids, including
urine. Urinary EVs have gained important recognition as potential diagnostic biomarkers in …

[HTML][HTML] Extracellular vesicles in renal physiology and clinical applications for renal disease

SH Kwon - The Korean journal of internal medicine, 2019 - ncbi.nlm.nih.gov
Many cells in the nephron release extracellular vesicles (EVs). EVs envelop nucleic acids,
proteins, and lipids. The surfaces of EVs express donor cell-specific markers, ligands, and …

Renal extracellular vesicles: from physiology to clinical application

EE Morrison, MA Bailey, JW Dear - The Journal of physiology, 2016 - Wiley Online Library
Urinary extracellular vesicles (uEVs) are released from all regions of the kidney's nephron
and from other cells that line the urinary tract. Extracellular vesicles retain proteomic and …