Skeletal muscle is the main tissue of lipid metabolism and accordingly is critical for
homeostasis and energy production; however, the determinants of lipid accumulation in …

In obesity, accumulation of lipid droplets in skeletal muscle fibers and a shift towards fast
muscle fiber types can both contribute to insulin resistance. However, it is not yet clear how …

The triglyceride content of skeletal muscle samples determined by lipid extraction correlates
with the severity of insulin-resistant glucose metabolism in muscle. To determine whether …

Objective To investigate whether differences in muscle fiber types affect early-stage fat
accumulation, under high fat diet challenge in mice. Methods Twelve healthy male C57BL/6 …

Dietary fat plays a major role in obesity, lipid metabolism, and cardiovascular diseases. To
determine whether the intake of different types of dietary fats affect the muscle fiber types …

A better understanding of skeletal muscle lipid metabolism is needed to identify the
molecular mechanisms relating intramuscular triglyceride (IMTG) to muscle metabolism and …

Endurance training enhances the capacity for fat oxidation during exercise due to increased
utilization of intramuscular lipid (IMCL). This study quantitatively investigated the impact of …

Key points Although lipid droplets in skeletal muscle are an important energy source during
endurance exercise, our understanding of lipid metabolism in this context remains …

Intramyocellular lipid (IMCL) is predominantly stored as intramuscular triglyceride (IMTG) in
lipid droplets and is utilized as metabolic fuel during physical exercise. IMTG is also …

Lipids in skeletal muscle play a fundamental role both in normal muscle metabolism and in
disease states. Skeletal muscle lipid accumulation is associated with several chronic …