The skeletal muscle is subjected to high mechanical and energetic demands. Lipid droplets
are an important source of energy substrates for the working muscle. Muscle cells contain a …

A better understanding of skeletal muscle lipid metabolism is needed to identify the
molecular mechanisms relating intramuscular triglyceride (IMTG) to muscle metabolism and …

Lipids stored in skeletal muscle cells are known as intramyocellular lipid (IMCL). Disorders
involving IMCL and its causative factor, circulatory free fatty acids (FFAs), induce a toxic state …

Despite over 50 years of research, a comprehensive understanding of how intramuscular
triglyceride (IMTG) is stored in skeletal muscle and its contribution as a fuel during exercise …

The lipid droplet (LD) is a universal organelle governing the storage and turnover of neutral
lipids. Mounting evidence indicates that elevated intramuscular triglyceride (IMTG) in …

Obesity and ensuing disorders are increasingly prevalent in young populations. Prolonged
exposure to high-fat diets (HFD) and excessive lipid accumulation were recently suggested …

Skeletal muscle energy metabolism has been a research focus of physiologists for more
than a century. Yet, how the use of intramuscular carbohydrate and lipid energy stores are …

Although skeletal muscle is recognized as a primary site of lipid utilization, the study of
muscle bioenergetics has focused mainly on carbohydrate, and consequently our …

The physiological dynamics of intramyocellular lipids (IMCLs) in different muscle types and
of hepatocellular lipids (HepCLs) are still uncertain. The dynamics of IMCLs in the soleus …

The lipid droplet (LD) is a central hub for fatty acid metabolism in cells. Here we define the
dynamics and explore the role of LDs in skeletal muscle satellite cells (SCs), a stem cell …