Objective Intramyocellular lipid (IMCL) is inversely related to insulin sensitivity in sedentary
populations, yet no prospective studies in humans have examined IMCL accumulation with …

Skeletal muscles consist of slow-twitch and fast-twitch muscle fibers, which have distinct
physiological and biochemical properties. The muscle fiber composition determines the …

Fat can be stored not only in adipose tissue but also in other tissues such as skeletal
muscle. Fat droplets accumulated in skeletal muscle [intramyocellular lipids (IMCLs)] can be …

The aim of the present study was to examine whether pretreatment with different fatty acids,
as well as the liver X receptor (LXR) agonist T0901317, could modify metabolic switching of …

The accumulation of intramyocellular lipid (IMCL) is recognized as an important determinant
of insulin resistance, and is increased by a high-fat diet (HFD). However, the effects of HFD …

Objective This study investigated the relationship between in vitro lipid content in myotubes
and in vivo whole body phenotypes of the donors such as insulin sensitivity, intramyocellular …

Muscle lipid stores and insulin sensitivity have a recognized association although the
mechanism remains unclear. We investigated how a 12‐week supervised combined …

Hormone-sensitive lipase (HSL), a key enzyme in fatty acid mobilization in adipocytes, has
been demonstrated also in skeletal muscle. To gain further insight into the role and …

In this study the distribution of intramyocellular lipids (IMCL) in human calf muscles was
determined by 1H-MR spectroscopic imaging (MRSI) measurements. An obstacle for MRSI …

The plasma membrane fatty acid transport protein FAT/CD36 is also present at the
mitochondria, where it may contribute to the regulation of fatty acid oxidation, although this …