Aims/hypothesis We examined in skeletal muscle (1) whether fatty acid transport protein
(FATP) 1 channels long-chain fatty acid (LCFA) to specific metabolic fates in rats; and (2) …

Factors that regulate intramuscular or muscle fat accumulation and breakdown and the sites
of muscle fat accumulation were reviewed. In particular, the regulation of intramuscular fat …

Extensive heterogeneity in myosin heavy chain and light chain (MLC) isoform expression in
skeletal muscle has been well documented in several mammalian species. The initial …

OBJECTIVE Chronic exercise and obesity both increase intramyocellular triglycerides
(IMTGs) despite having opposing effects on insulin sensitivity. We hypothesized that …

Apoptosis and autophagy are critical in normal skeletal muscle homeostasis; however,
dysregulation can lead to muscle atrophy and dysfunction. Lipotoxicity and/or lipid …

New Findings What is the topic of this review? This report addresses novel mechanisms
regulating the utilization of long‐chain fatty acids, with emphasis on FAT/CD36 and lipolysis …

Objectives: To address the potential effects of weight loss and physical activity (WL+ Ex) on
intramyocellular lipid (IMCL) and lipid droplet size in overweight and obese previously …

Vertebrate skeletal myofibers are heterogeneous with respect to their metabolic, contractile
and morphological properties. To better understand skeletal myofiber diversity and plasticity …

Myosin heavy chain (MHC) mediates the metabolic and contractile responses of skeletal
muscles. MHC displays different isoforms, each of which has different characteristics. To …

It was hypothesized that transcriptional reprogramming is involved in the structural and
functional adaptations of lipid metabolism in human tibialis anterior muscle (TA) from …