Post-transcriptional regulation of gene expression enables cells to fine-tune the expression
of a protein in a spatial and temporal manner. This regulation is mediated by the binding of …

Abstract mRNA stability is the mechanism by which cells protect transcripts allowing their
expression to execute various functions that affect cell metabolism and fate. It is well …

In this report, we investigate the role of the RNA-binding protein HuR during skeletal
myogenesis. At the onset of myogenesis in differentiating C2C12 myocytes and in vivo in …

The formation of muscle fibers involves the sequential expression of many proteins that
regulate key steps during myoblast-to-myotube transition. MyoD, myogenin, and the cyclin …

The ubiquitous mRNA-binding protein human antigen R (HuR) and its neuronal relatives
(HuB, HuC, HuD) participate in the post-transcriptional regulation of many AU-rich element …

The RNA‐binding protein HuR (human antigen R) associates with numerous transcripts,
coding and noncoding, and controls their splicing, localization, stability, and translation …

The RNA-binding proteins involved in regulation of mRNA post-transcriptional processing
and translation control the fates of thousands of mRNA transcripts and basic cellular …

Myogenesis, the process of muscle fiber formation and regeneration, is activated during
embryogenesis and in response to muscle injury to ensure normal growth and repair of …

HuR/ELAVL1 is an RNA-binding protein involved in differentiation and stress response that
acts primarily by stabilizing messenger RNA (mRNA) targets. HuR comprises three RNA …

The elaborate interplay of coding and noncoding factors governs muscle growth and
development. Here, we reported a mutual activation between long noncoding RNA (lncRNA) …