MyoD acetylation influences temporal patterns of skeletal muscle gene expression

M Di Padova, G Caretti, P Zhao, EP Hoffman… - Journal of biological …, 2007 - ASBMB
MyoD is sufficient to initiate the skeletal muscle gene expression program. Transcription of
certain MyoD target genes occurs in the early phases, whereas that of others is induced only …

Cytoskeleton-dependent transport as a potential target for interfering with post-transcriptional HuR mRNA regulons

W Eberhardt, A Badawi, A Biyanee… - Frontiers in …, 2016 - frontiersin.org
The ubiquitous mRNA binding protein human antigen R (HuR), a member of the embryonal
lethal abnormal vision protein family has a critical impact on the post-transcriptional control …

Signalling pathways regulating nucleo-cytoplasmic shuttling of the mRNA-binding protein HuR

A Doller, J Pfeilschifter, W Eberhardt - Cellular signalling, 2008 - Elsevier
During the last decade evidence from numerous studies has been accumulated
demonstrating that posttranscriptional gene regulation including mRNA turnover and …

Forget transcription: translation is where the action is

LB Maggi Jr, JD Weber - Molecular and cellular biology, 2013 - Am Soc Microbiol
The flow of genetic information from the genome through RNA and finally into protein has
numerous regulatory steps. Recent studies have shed light upon the complexity of the …

[PDF][PDF] HuD is a neural translation enhancer acting on mTORC1-responsive genes and counteracted by the Y3 small non-coding RNA

T Tebaldi, P Zuccotti, D Peroni, M Köhn, L Gasperini… - Molecular cell, 2018 - cell.com
The RNA-binding protein HuD promotes neurogenesis and favors recovery from peripheral
axon injury. HuD interacts with many mRNAs, altering both stability and translation …

MicroRNA-378 targets the myogenic repressor MyoR during myoblast differentiation

J Gagan, BK Dey, R Layer, Z Yan, A Dutta - Journal of Biological Chemistry, 2011 - ASBMB
MicroRNAs play important roles in many cell processes, including the differentiation process
in several different lineages. For example, microRNAs can promote differentiation by …

Genomic analyses of the RNA-binding protein Hu antigen R (HuR) identify a complex network of target genes and novel characteristics of its binding sites

PJ Uren, SC Burns, J Ruan, KK Singh, AD Smith… - Journal of Biological …, 2011 - ASBMB
The ubiquitously expressed RNA-binding protein Hu antigen R (HuR) or ELAVL1 is
implicated in a variety of biological processes as well as being linked with a number of …

Insights from the HuR-interacting transcriptome: ncRNAs, ubiquitin pathways, and patterns of secondary structure dependent RNA interactions

G St Laurent, D Shtokalo, M Heydarian… - Molecular genetics and …, 2012 - Springer
The HuR protein regulates the expression of thousands of cellular transcripts by modulating
mRNA splicing, trafficking, translation, and stability. Although it serves as a model of RNA …

RNA-dependent association with myosin IIA promotes F-actin-guided trafficking of the ELAV-like protein HuR to polysomes

A Doller, S Schulz, J Pfeilschifter… - Nucleic acids …, 2013 - academic.oup.com
The role of the mRNA-binding protein human antigen R (HuR) in stabilization and
translation of AU-rich elements (ARE) containing mRNAs is well established. However, the …

Regulation of HuR structure and function by dihydrotanshinone-I

P Lal, L Cerofolini, VG D'Agostino, C Zucal… - Nucleic acids …, 2017 - academic.oup.com
The Human antigen R protein (HuR) is an RNA-binding protein that recognizes U/AU-rich
elements in diverse RNAs through two RNA-recognition motifs, RRM1 and RRM2, and post …