Skeletal muscle gene expression is governed by the myogenic regulatory family (MRF)
which includes MyoD (MYOD1) and myogenin (MYOG). MYOD1 and MYOG are known to …

The control of eukaryotic gene expression occurs at multiple levels, from transcription to
messenger RNA processing, transport, localization, turnover, and translation. RNA-binding …

The muscle determination gene MyoD is essential for normal development of hypaxial
musculature in vertebrate embryos and plays a unique role in skeletal muscle regeneration …

Posttranscriptional gene regulation by RNA binding proteins (RBPs) and their microRNA
(miRNAs) partners is known to affect 50% of genes during T cell activation. The RBP, HuR …

YB-1 is a broad-specificity RNA-binding protein that is involved in regulation of mRNA
transcription, splicing, translation, and stability. In both germinal and somatic cells, YB-1 and …

MyoD is a master regulator of the skeletal muscle gene expression program. ChIP-Seq
analysis has recently revealed that MyoD binds to a large number of genomic loci in …

Skeletal muscle differentiation is orchestrated by a network of transcription factors,
epigenetic regulators, and non‐coding RNAs. The transcription factor Yin Yang 1 (YY1) …

Human antigen R (HuR) is an RNA binding protein mainly involved in maintaining the
stability and controlling the translation of mRNAs, critical for immune response, cell survival …

Since their discovery as key regulators of early animal development, microRNAs now are
recognized as widespread regulators of gene expression. Despite their abundance, little is …

Background The discordance between steady-state levels of mRNAs and protein has been
attributed to posttranscriptional control mechanisms affecting mRNA stability and translation …