DNA photocleavage in the near-infrared wavelength range by 2-quinolinium dicarbocyanine dyes

EO Ahoulou, KK Drinkard, K Basnet, A St. Lorenz… - Molecules, 2020 - mdpi.com
Here, we report the syntheses of two pentamethine cyanine dyes containing quinolinium
rings and substituted with either hydrogen (3) or bromine (4) at the meso carbon. The …

Single photon DNA photocleavage at 830 nm by quinoline dicarbocyanine dyes

K Basnet, T Fatemipouya, AS Lorenz… - Chemical …, 2019 - pubs.rsc.org
We have synthesized symmetrical carbocyanine dyes in which two 4-quinolinium rings are
joined by a pentamethine bridge that is meso-substituted with H or Cl. Irradiation of the …

Oxidative cleavage of DNA by pentamethine carbocyanine dyes irradiated with long-wavelength visible light

CT Mapp, EA Owens, M Henary, KB Grant - Bioorganic & Medicinal …, 2014 - Elsevier
Here we report the synthesis of seven symmetrical carbocyanine dyes in which two nitrogen-
substituted benz [e] indolium rings are joined by a pentamethine bridge that is meso …

Accelerated photobleaching of a cyanine dye in the presence of a ternary target DNA, PNA probe, dye catalytic complex: a molecular diagnostic

M Wang, R Holmes-Davis, Z Rafinski… - Analytical …, 2009 - ACS Publications
In many settings, molecular testing is needed but unavailable due to complexity and cost.
Simple, rapid, and specific DNA detection technologies would provide important alternatives …

Synthesis and Investigation of the DNA‐Binding and DNA‐Photodamaging Properties of Indolo[2,3‐b]quinolizinium Bromide

H Ihmels, K Faulhaber, K Wissel… - European Journal of …, 2001 - Wiley Online Library
The readily available cationic dye 3‐Br binds to DNA as was shown by UV, fluorescence
and CD spectroscopy. The electronic spectra of the quinolizinium salt 3 exhibit significant …

Indotricarbocyanine dyes relevant for photodynamic therapy and their radicals: Substituent effects studied by optical and electrochemical methods

N Belko, H Maltanava, A Lugovski, M Shundalau… - Dyes and …, 2023 - Elsevier
Photodynamic therapy is an effective and minimally invasive treatment method for cancer. A
deeper understanding of the photocytotoxicity mechanism of cyanine dyes is necessary for …

Photobleaching of asymmetric cyanines used for fluorescence imaging of single DNA molecules

C Kanony, B Åkerman, E Tuite - Journal of the American Chemical …, 2001 - ACS Publications
The photobleaching of the cyanine dyes YO and YOYO has been investigated for both free
and DNA-bound dyes, using absorption and fluorescence spectroscopy coupled with …

Indolo[2,3‐b]‐Quinolizinium Bromide: An Efficient Intercalator with DNA‐Photodamaging Properties

G Viola, F Dall′ Acqua, N Gabellini, S Moro… - …, 2002 - Wiley Online Library
The associative interactions of indolo [2, 3‐b]‐quinolizinium bromide with DNA and its DNA
photocleavage properties were studied in detail. Absorption and emission spectroscopy …

Cationic anthraquinone derivatives as catalytic DNA photonucleases: mechanisms for DNA damage and quinone recycling

B Armitage, C Yu, C Devadoss… - Journal of the American …, 1994 - ACS Publications
Ammonium-substituted anthraquinone derivatives have been found to catalyze DNA
cleavage upon irradiation with 350 nm light. Picosecond laser spectroscopy demonstrates …

Two-photon absorption of copper tetrasulfophthalocyanine induces phototoxicity towards Jurkat cells in vitro

Y Mir, D Houde, JE van Lier - Photochemical & Photobiological Sciences, 2006 - Springer
The feasibility to induce oxygen-independent tumour cell kill by two-photon excitation of
copper tetrasulfophthalocyanine (CuPcS 4) was studied in Jurkat cells in vitro. Following …