Development and characterization of novel dendritic cell (DC)-targeting vaccine against human immunodeficiency virus (HIV)-1 envelope conserved elements (CEs)
M Mahmoudi - 2021 - mspace.lib.umanitoba.ca
Abstract Development of the human immunodeficiency virus type-1 (HIV-1) vaccine is an
effective and powerful prevention method of the halting pandemic of the acquired …
effective and powerful prevention method of the halting pandemic of the acquired …
Development and evaluation of an Ebola virus glycoprotein mucin-like domain replacement system as a new dendritic cell-targeting vaccine approach against HIV-1
Z Ao, L Wang, H Azizi, TA Olukitibi, G Kobinger… - Journal of …, 2021 - Am Soc Microbiol
The development of efficient vaccine approaches against HIV infection remains challenging
in the vaccine field. Here, we developed an Ebola virus envelope glycoprotein (EboGP) …
in the vaccine field. Here, we developed an Ebola virus envelope glycoprotein (EboGP) …
[HTML][HTML] Incorporation of Ebola glycoprotein into HIV particles facilitates dendritic cell and macrophage targeting and enhances HIV-specific immune responses
The development of an effective vaccine against HIV infection remains a global priority.
Dendritic cell (DC)-based HIV immunotherapeutic vaccine is a promising approach which …
Dendritic cell (DC)-based HIV immunotherapeutic vaccine is a promising approach which …
[HTML][HTML] Dendritic cells/macrophages-targeting feature of Ebola glycoprotein and its potential as immunological facilitator for antiviral vaccine approach
In the prevention of epidemic and pandemic viral infection, the use of the antiviral vaccine
has been the most successful biotechnological and biomedical approach. In recent times …
has been the most successful biotechnological and biomedical approach. In recent times …
Immunogenicity testing of a novel engineered HIV-1 envelope gp140 DNA vaccine construct
S Kumar, J Yan, K Muthumani… - DNA and cell …, 2006 - liebertpub.com
DNA vaccines expressing the envelope (env) of the human immunodeficiency virus type 1
(HIV-1) have been relatively ineffective at generating strong immune responses. In this …
(HIV-1) have been relatively ineffective at generating strong immune responses. In this …
Immunogenicity of virus-like particles containing modified human immunodeficiency virus envelope proteins
Extensive glycosylation and variable loops of the HIV envelope protein (Env) are reported to
shield some neutralizing epitopes. Here, we investigated the immunogenicity of mutated HIV …
shield some neutralizing epitopes. Here, we investigated the immunogenicity of mutated HIV …
Immunogenicity of a novel engineered HIV-1 clade C synthetic consensus-based envelope DNA vaccine
J Yan, N Corbitt, P Pankhong, T Shin, A Khan… - Vaccine, 2011 - Elsevier
DNA vaccines require significant engineering in order to generate strong CTL responses in
both non-human primates and humans. In this study, we designed a clade C env gene …
both non-human primates and humans. In this study, we designed a clade C env gene …
[HTML][HTML] Induction of HIV neutralizing antibodies against the MPER of the HIV envelope protein by HA/gp41 chimeric protein-based DNA and VLP vaccines
L Ye, Z Wen, K Dong, X Wang, Z Bu, H Zhang… - PloS one, 2011 - journals.plos.org
Several conserved neutralizing epitopes have been identified in the HIV Env protein and
among these, the MPER of gp41 has received great attention and is widely recognized as a …
among these, the MPER of gp41 has received great attention and is widely recognized as a …
Construction and evaluation of DNA vaccine encoding Ebola virus glycoprotein fused with lysosome-associated membrane protein
Y Liu, B Sun, J Pan, Y Feng, W Ye, J Xu, M Lan, H Sun… - Antiviral Research, 2021 - Elsevier
Ebola virus (EBOV) of the genus Ebolavirus belongs to the family Filoviridae, which cause
disease in both humans and non-human primates. Zaire Ebola virus accounts for the highest …
disease in both humans and non-human primates. Zaire Ebola virus accounts for the highest …
A novel mechanism of immune evasion mediated by Ebola virus soluble glycoprotein
CF Basler - Expert review of anti-infective therapy, 2013 - Taylor & Francis
Evaluation of: Mohan GS, Li W, Ye L, Compans RW, Yang C. Antigenic subversion: a novel
mechanism of host immune evasion by Ebola virus. PLoS Pathog. 8 (12), e1003065 (2012) …
mechanism of host immune evasion by Ebola virus. PLoS Pathog. 8 (12), e1003065 (2012) …