Myotubes are mature muscle cells that form the basic structural element of skeletal muscle.
When stretching skeletal muscles, myotubes are subjected to passive tension as well. This …

Background/Aim: Mechanical loading of differentiated myoblasts in vitro may mimic loading
patterns of skeletal muscle in vivo. However, it is still uncharacterized the loading conditions …

Cyclic stretch of differentiated myotubes mimics the loading pattern of mature skeletal
muscle. We tested a cell culture model of disuse atrophy by the cessation of repetitive bouts …

Mechanical signals are critical to the growth and maintenance of skeletal muscle, but the
mechanism by which these signals are transduced by the cell remains unknown. This work …

Skeletal muscle fibers have the ability to increase their size in response to a mechanical
overload. Finite element modeling data suggest that mechanically loaded muscles in vivo …

The behavior of cells and tissues in vivo is determined by the integration of multiple
biochemical and mechanical signals. Of the mechanical signals, stretch has been studied for …

Cyclic mechanical stimulation has been found to deeply affect cell behavior in terms of
cytoskeleton remodeling, signaling pathway alteration and differential gene expression in …

Many tissues in our body have a tubular shape and are constantly exposed to various
stresses. Luminal pressure imposes tension on the epithelial and myoepithelial or smooth …

Several lines of evidence suggest that muscle cells can distinguish between specific
mechanical stimuli. To test this concept, we subjected C2C12 myotubes to cyclic uniaxial or …

Wednesday, February 29, 2012 719a showed more non-muscle myosin IIb. Mechanical
induction was mediated via focal adhesions; vinculin assembled earlier in ASCs. Inhibiting …