Yeast U6 snRNA made by RNA polymerase II is less stable but functional
U6 small nuclear (sn) RNA is the shortest and most conserved snRNA in the spliceosome
and forms a substantial portion of its active site. Unlike the other four spliceosomal snRNAs …
and forms a substantial portion of its active site. Unlike the other four spliceosomal snRNAs …
In vitro assembly of yeast U6 snRNP: a functional assay.
P Fabrizio, DS McPheeters, J Abelson - Genes & Development, 1989 - genesdev.cshlp.org
U6 small nuclear RNA (snRNA) is the most highly conserved spliceosomal RNA, and it has
been postulated to have a fundamental role in pre-mRNA splicing. To elucidate this role, we …
been postulated to have a fundamental role in pre-mRNA splicing. To elucidate this role, we …
A stem/loop in U6 RNA defines a conformational switch required for pre-mRNA splicing.
DM Fortner, RG Troy, DA Brow - Genes & development, 1994 - genesdev.cshlp.org
U6 small nuclear RNA (snRNA) is an essential component of the spliceosome, the
ribonucleoprotein complex that carries out the splicing of pre-mRNAs. The precise function …
ribonucleoprotein complex that carries out the splicing of pre-mRNAs. The precise function …
RNA structure and RNA–protein interactions in purified yeast U6 snRNPs
R Karaduman, P Fabrizio, K Hartmuth, H Urlaub… - Journal of molecular …, 2006 - Elsevier
The U6 small nuclear RNA (snRNA) undergoes major conformational changes during the
assembly of the spliceosome and catalysis of splicing. It associates with the specific protein …
assembly of the spliceosome and catalysis of splicing. It associates with the specific protein …
[HTML][HTML] Characterization of Sm-like proteins in yeast and their association with U6 snRNA
Seven Sm proteins associate with U1, U2, U4 and U5 spliceosomal snRNAs and influence
snRNP biogenesis. Here we describe a novel set of Sm-like (Lsm) proteins in …
snRNP biogenesis. Here we describe a novel set of Sm-like (Lsm) proteins in …
Conserved domains of human U4 snRNA required for snRNP and spliceosome assembly
C Wersig, A Bindereif - Nucleic acids research, 1990 - academic.oup.com
U4 snRNA is phylogenetically highly conserved and organized in several domains. To
determine the function of each of the domains of human U4 snRNA in the multi-step process …
determine the function of each of the domains of human U4 snRNA in the multi-step process …
The conserved central domain of yeast U6 snRNA: importance of U2-U6 helix Ia in spliceosome assembly
DE Ryan, J Abelson - Rna, 2002 - cambridge.org
In the pre-mRNA processing machinery of eukaryotic cells, U6 snRNA is located at or near
the active site for pre-mRNA splicing catalysis, and U6 is involved in catalyzing the first …
the active site for pre-mRNA splicing catalysis, and U6 is involved in catalyzing the first …
The phylogenetically invariant ACAGAGA and AGC sequences of U6 small nuclear RNA are more tolerant of mutation in human cells than in Saccharomyces …
B Datta, AM Weiner - Molecular and cellular biology, 1993 - Taylor & Francis
U6 small nuclear RNA (snRNA) is the most highly conserved of the five spliceosomal
snRNAs that participate in nuclear mRNA splicing. The proposal that U6 snRNA plays a key …
snRNAs that participate in nuclear mRNA splicing. The proposal that U6 snRNA plays a key …
U4 small nuclear RNA can function in both the major and minor spliceosomes
GC Shukla, RA Padgett - Proceedings of the National …, 2004 - National Acad Sciences
U4 small nuclear RNA (snRNA) and U6 snRNA form a base-paired di-snRNP complex that
is essential for pre-mRNA splicing of the major class of metazoan nuclear introns. The …
is essential for pre-mRNA splicing of the major class of metazoan nuclear introns. The …
Identification and characterization of Uss1p (Sdb23p): a novel U6 snRNA‐associated protein with significant similarity to core proteins of small nuclear …
M Cooper, LH Johnston, JD Beggs - The EMBO journal, 1995 - embopress.org
The SDB23 gene of Saccharomyces cerevisiae was isolated in a search for high copy‐
number suppressors of mutations in a cell cycle gene, DBF2, SDB23 encodes a 21,276 Da …
number suppressors of mutations in a cell cycle gene, DBF2, SDB23 encodes a 21,276 Da …