Background Longitudinal EEG recorded by implanted devices is critical for understanding
and managing epilepsy. Recent research reports patient-specific, multi-day cycles in device …

The cyclical structure of epilepsy was recently (re)-discovered through years-long
intracranial electroencephalography (EEG) obtained with implanted devices. In this review …

Introduction Implanted neurostimulation devices are gaining traction as therapeutic options
for people with certain forms of drug-resistant focal epilepsy. Some of these devices enable …

Many biological processes are modulated by rhythms on circadian and multidien timescales.
In focal epilepsy, various seizure features, such as spread and duration, can change from …

Epilepsy is defined by the seemingly random occurrence of spontaneous seizures. The
ability to anticipate seizures would enable preventative treatment strategies. A central but …

Objective Epilepsy is a chronic disorder, but seizure recordings are usually obtained in the
acute setting. The chronic behavior of seizures and the interictal bursts that sometimes …

The current paradigm for treatment of epilepsy begins with trials of antiepileptic drugs,
followed by evaluation for resective brain surgery in drug-resistant patients. If surgery is not …

Purpose To determine the feasibility of using epileptiform events detected by continuous
electrocorticographic monitoring via a brain-responsive neurostimulation system to …

Importance Focal epilepsy is characterized by the cyclical recurrence of seizures, but, to our
knowledge, the prevalence and patterns of seizure cycles are unknown. Objective To …

Objective Despite the overall success of responsive neurostimulation (RNS) therapy for drug‐
resistant focal epilepsy, clinical outcomes in individuals vary significantly and are hard to …