Dementia with L ewy bodies: early diagnostic challenges

H Fujishiro, E Iseki, S Nakamura, K Kasanuki… - …, 2013 - Wiley Online Library
Dementia with L ewy bodies (DLB) is defined pathologically as neurodegeneration
associated with L ewy bodies (LB). LB‐related symptoms, including olfactory dysfunction …

Metabolic patterns across core features in dementia with lewy bodies

S Morbelli, A Chincarini, M Brendel… - Annals of …, 2019 - Wiley Online Library
Objective To identify brain regions whose metabolic impairment contributes to dementia with
Lewy bodies (DLB) clinical core features expression and to assess the influence of severity …

Clinical features of Alzheimer disease with and without Lewy bodies

EJ Chung, GM Babulal, SE Monsell, NJ Cairns… - JAMA …, 2015 - jamanetwork.com
Importance Lewy bodies are a frequent coexisting pathology in late-onset Alzheimer
disease (AD). Previous studies have examined the contribution of Lewy bodies to the clinical …

Quantifying fluctuation in dementia with Lewy bodies, Alzheimer's disease, and vascular dementia

MP Walker, GA Ayre, JL Cummings, K Wesnes… - Neurology, 2000 - AAN Enterprises
Background: Case reports and clinical observations suggest that fluctuating cognition (FC) is
common in the major dementias, particularly dementia with Lewy bodies (DLB), where it is …

Cerebrospinal fluid Alzheimer's disease biomarkers across the spectrum of Lewy body diseases: results from a large multicenter cohort

I Van Steenoven, D Aarsland… - Journal of …, 2016 - content.iospress.com
Background: Concomitant Alzheimer's disease (AD) pathology is observed in Lewy body
diseases (LBD), but the clinical impact is unknown. Only a few biomarker studies in LBD …

Clinico‐pathological comparison of patients with autopsy‐confirmed Alzheimer's disease, dementia with Lewy bodies, and mixed pathology

A Chatterjee, V Hirsch‐Reinshagen… - Alzheimer's & …, 2021 - Wiley Online Library
Abstract Introduction Patients with Alzheimer's disease (AD) and dementia with Lewy bodies
(DLB) frequently demonstrate coexistent AD neuropathological change (ADNC) and Lewy …

Hippocampal volumes predict risk of dementia with Lewy bodies in mild cognitive impairment

K Kantarci, T Lesnick, TJ Ferman, SA Przybelski… - Neurology, 2016 - AAN Enterprises
Objective: To predict the risk of probable dementia with Lewy bodies (DLB) competing with
Alzheimer disease (AD) dementia by hippocampal volume (HV) in patients with mild …

18F-fluorodeoxyglucose positron emission tomography in dementia with Lewy bodies

J Graff-Radford, TG Lesnick, R Savica… - Brain …, 2020 - academic.oup.com
Among individuals with dementia with Lewy bodies, pathologic correlates of clinical course
include the presence and extent of coexisting Alzheimer's pathology and the presence of …

[HTML][HTML] In vivo nucleus basalis of Meynert degeneration in mild cognitive impairment with Lewy bodies

J Schumacher, JP Taylor, CA Hamilton, M Firbank… - NeuroImage: Clinical, 2021 - Elsevier
Objectives To investigate in vivo degeneration of the cholinergic system in mild cognitive
impairment with Lewy bodies (MCI-LB), we studied nucleus basalis of Meynert (NBM) …

The Mini‐Mental State exam may help in the differentiation of dementia with Lewy bodies and Alzheimer's disease

TA Ala, LF Hughes, GA Kyrouac… - … journal of geriatric …, 2002 - Wiley Online Library
Objective Since patients with dementia with Lewy bodies (DLB) tend to have greater
impairment of attention and construction and better memory ability on neuropsychological …