Mapping of low molecular weight heparins using reversed phase ion pair liquid chromatography–mass spectrometry
D Li, L Chi, L Jin, X Xu, X Du, S Ji, L Chi - Carbohydrate polymers, 2014 - Elsevier
Low molecular weight heparins (LMWHs) are structurally complex, highly sulfated and
negatively charged, linear carbohydrate polymers prepared by chemical or enzymatic …
negatively charged, linear carbohydrate polymers prepared by chemical or enzymatic …
Fragment profiling of low molecular weight heparins using reversed phase ion pair liquid chromatography-electrospray mass spectrometry
X Xu, D Li, L Chi, X Du, X Bai, L Chi - Carbohydrate research, 2015 - Elsevier
Low molecular weight heparins (LMWHs) are linear and highly charged carbohydrate
polymers prepared by chemical or enzymatic depolymerization of heparin. Compared to …
polymers prepared by chemical or enzymatic depolymerization of heparin. Compared to …
Bottom-up low molecular weight heparin analysis using liquid chromatography-Fourier transform mass spectrometry for extensive characterization
G Li, J Steppich, Z Wang, Y Sun, C Xue… - Analytical …, 2014 - ACS Publications
Low molecular weight heparins (LMWHs) are heterogeneous, polydisperse, and highly
negatively charged mixtures of glycosaminoglycan chains prescribed as anticoagulants. The …
negatively charged mixtures of glycosaminoglycan chains prescribed as anticoagulants. The …
Profiling analysis of low molecular weight heparins by multiple heart-cutting two dimensional chromatography with quadruple time-of-flight mass spectrometry
Y Ouyang, Y Zeng, Y Rong, Y Song, L Shi… - Analytical …, 2015 - ACS Publications
Low molecular weight heparins (LMWHs) are polydisperse and microheterogenous mixtures
of polysaccharides used as anticoagulant drugs. Profiling analysis is important for obtaining …
of polysaccharides used as anticoagulant drugs. Profiling analysis is important for obtaining …
Liquid chromatography–diode array detection–mass spectrometry for compositional analysis of low molecular weight heparins
Z Wang, D Li, X Sun, X Bai, L Jin, L Chi - Analytical biochemistry, 2014 - Elsevier
Low molecular weight heparins (LMWHs) are important artificial preparations from heparin
polysaccharide and are widely used as anticoagulant drugs. To analyze the structure and …
polysaccharide and are widely used as anticoagulant drugs. To analyze the structure and …
Sequencing the oligosaccharide pool in the low molecular weight heparin dalteparin with offline HPLC and ESI–MS/MS
Low molecular weight heparins (LMWHs) are widely used anticoagulant drugs. The
composition and sequence of LMWH oligosaccharides determine their safety and efficacy …
composition and sequence of LMWH oligosaccharides determine their safety and efficacy …
Top-down approach for the direct characterization of low molecular weight heparins using LC-FT-MS
Low molecular heparins (LMWHs) are structurally complex, heterogeneous, polydisperse,
and highly negatively charged mixtures of polysaccharides. The direct characterization of …
and highly negatively charged mixtures of polysaccharides. The direct characterization of …
Recent advances in mass spectrometry analysis of low molecular weight heparins
Z Wang, L Chi - Chinese Chemical Letters, 2018 - Elsevier
Carbohydrates are important biomolecules and promising novel drug candidates, but their
structural complexity and heterogeneity hinder their study and application. Low molecular …
structural complexity and heterogeneity hinder their study and application. Low molecular …
Reversed-phase ion-pair ultra-high-performance-liquid chromatography–mass spectrometry for fingerprinting low-molecular-weight heparins
DJ Langeslay, E Urso, C Gardini, A Naggi… - … of Chromatography A, 2013 - Elsevier
Heparin is a complex mixture of sulfated linear carbohydrate polymers. It is widely used as
an antithrombotic drug, though it has been shown to have a myriad of additional biological …
an antithrombotic drug, though it has been shown to have a myriad of additional biological …
Complete molecular weight profiling of low-molecular weight heparins using size exclusion chromatography-ion suppressor-high-resolution mass spectrometry
Low-molecular weight heparins (LMWH) prepared by partial depolymerization of
unfractionated heparin are used globally to treat coagulation disorders on an outpatient …
unfractionated heparin are used globally to treat coagulation disorders on an outpatient …
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