Immunomodulatory effects in the spleen‐injured mice following exposure to titanium dioxide nanoparticles

X Sang, M Fei, L Sheng, X Zhao, X Yu… - … Research Part A, 2014 - Wiley Online Library
Immune injuries following the exposure of titanium dioxide nanoparticles (TiO2 NPs) have
been greatly concerned along with the TiO2 NPs are widely used in pharmacology and daily …

The chronic spleen injury of mice following long‐term exposure to titanium dioxide nanoparticles

X Sang, L Zheng, Q Sun, N Li, Y Cui… - … research Part A, 2012 - Wiley Online Library
To understand the chronic spleen injury induced by intragastric administrations with 2.5, 5,
and 10 mg kg− 1 body weight titanium dioxide nanoparticles (TiO2 NPs) for 90 consecutive …

Nano-sized titanium dioxide-induced splenic toxicity: A biological pathway explored using microarray technology

L Sheng, L Wang, X Sang, X Zhao, J Hong… - Journal of Hazardous …, 2014 - Elsevier
Abstract Titanium dioxide nanoparticles (TiO 2 NPs) have been widely used in various
areas, and its potential toxicity has gained wide attention. However, the molecular …

Spleen injury and apoptotic pathway in mice caused by titanium dioxide nanoparticules

N Li, Y Duan, M Hong, L Zheng, M Fei, X Zhao, J Wang… - Toxicology letters, 2010 - Elsevier
Nanoparticulate titanium dioxide (TiO2) has been demonstrated to decrease immunity of
mice, but very little is known about the injury of spleen involved immunomodulation and its …

Role of macrophage (M1 and M2) in titanium-dioxide nanoparticle-induced oxidative stress and inflammatory response in rat

S Kumar, R Meena, R Paulraj - Applied biochemistry and biotechnology, 2016 - Springer
Titanium-dioxide nanoparticles (TNP) are used in various consumable goods. Evidence has
demonstrated the cytotoxicity of TNPs, but exact mechanism is yet to be elucidated. The …

Protective effect of N-acetylcystiene against titanium dioxide nanoparticles modulated immune responses in male albino rats

MM Soliman, HF Attia, MM Hussein… - American journal of …, 2013 - ksascholar.dri.sa
The protective effects of N-acetylcysteine (NAC) against orally administered titanium dioxide
nanoparticles (TiO 2) for 3 months on male albino rats were examined. Adult male albino …

Systemic immune effects of titanium dioxide nanoparticles after repeated intratracheal instillation in rat

Y Fu, Y Zhang, X Chang, Y Zhang, S Ma, J Sui… - International journal of …, 2014 - mdpi.com
The potential immune effects of titanium dioxide nanoparticles (nano-TiO2) are raising
concern. Our previous study verified that nano-TiO2 induce local immune response in lung …

An increase in mouse tumor growth by an in vivo immunomodulating effect of titanium dioxide nanoparticles

EY Moon, GH Yi, JS Kang, JS Lim… - Journal of …, 2011 - Taylor & Francis
Here, we investigated whether titanium dioxide (TiO2) nanoparticles affect in vivo tumor
growth through the modulation of mononuclear leukocytes. In vitro lymphocyte proliferation …

The toxicological effects of nano titanium dioxide on target organs and mechanisms of toxicity

C Li, M Tang - Journal of applied toxicology, 2024 - Wiley Online Library
Abstract Nano‐titanium dioxide (TiO2NPs) is widely used for its extremely high stability,
corrosion resistance, and photocatalytic properties and has penetrated into various fields of …

Signaling pathway of inflammatory responses in the mouse liver caused by TiO2 nanoparticles

Y Cui, H Liu, M Zhou, Y Duan, N Li… - … Research Part A, 2011 - Wiley Online Library
In an effort to examine signaling pathway of inflammation of the mouse liver caused by
intragastric administration of titanium dioxide nanoparticles (NPs), we assessed Toll‐like …