Our study aimed to describe the population pharmacokinetics (PK) of piperacillin and
tazobactam in patients on extracorporeal membrane oxygenation (ECMO), with and without …

Critical illness and extracorporeal circulation, such as extracorporeal membrane
oxygenation (ECMO) and continuous renal replacement therapy (CRRT), may alter the …

Objectives To explore extracorporeal membrane oxygenation (ECMO)-related alterations of
the pharmacokinetics (PK) of piperacillin/tazobactam and determine an optimal dosage …

Background Extracorporeal membrane oxygenation (ECMO) is a life-saving modality but
has the potential to alter the pharmacokinetics (PK) of antimicrobials. Imipenem/cilastatin …

Objectives To describe the impact of extracorporeal membrane oxygenation (ECMO)
devices on piperacillin exposure in ICU patients. Methods This observational, prospective …

Carbapenem pharmacokinetic (PK) profiles are significantly different in critically ill patients
because of the drastic variability of the patients' physiological parameters. Published …

Background Extracorporeal membrane oxygenation (ECMO), a cardiopulmonary bypass
device, has been found to increase the profound pathophysiological changes associated …

What is known and objective Extracorporeal membrane oxygenation (ECMO) is a life‐saving
system used for critically ill patients with cardiac and/or respiratory failure. The …

Background Extracorporeal membrane oxygenation (ECMO) is increasingly used in
intensive care units and can modify drug pharmacokinetics and lead to under-exposure …

An advanced understanding of the pharmacokinetic alterations in critically ill patients
receiving ECMO is essential to provide optimal antibiotic dosing in these complex patients …