The increasing prevalence of persistent biofilm infections, such as wound infections, chronic
lung infections or medical device-related infections, which usually tolerate conventional …

The great clinical significance of biofilm-associated infections and their inherent
recalcitrance to antibiotic treatment urgently demand the development of novel antibiofilm …

Bacterial resistance to commonly used drugs has become a global health problem, causing
increased infection cases and mortality rate. One of the main virulence determinants in many …

The formation of surface-attached cellular agglomerates, the so-called biofilms, contributes
significantly to bacterial resistance to antibiotics and innate host defenses. Bacterial biofilms …

Lately, antimicrobial resistance (AMR) is increasing at an exponential rate making it
important to search alternatives to antibiotics in order to combat multi-drug resistant (MDR) …

Biofilm-associated infections represent one of the major threats of modern medicine. Biofilm-
forming bacteria are encased in a complex mixture of extracellular polymeric substances …

It is widely recognized that many chronic infections of the human body have a polymicrobial
etiology. These include diabetic foot ulcer infections, lung infections in cystic fibrosis …

Microbial cells show a strong natural tendency to adhere to surfaces and to colonize them by
forming complex communities called biofilms. In this growth mode, biofilm-forming cells …

Antimicrobial peptides (AMPs) have a broad spectrum of activity and unspecific mechanisms
of action. Therefore, they are seen as valid alternatives to overcome clinically relevant …

Bacterial resistance is an emergency public health problem worldwide, compounded by the
ability of bacteria to form biofilms, mainly in seriously ill hospitalized patients. The World …