Natural products in atherosclerosis therapy by targeting PPARs: a review focusing on lipid metabolism and inflammation
Y Zhang, XY Zhang, SR Shi, CN Ma, YP Lin… - Frontiers in …, 2024 - frontiersin.org
Inflammation and dyslipidemia are critical inducing factors of atherosclerosis. Peroxisome
proliferator-activated receptors (PPARs) are ligand-activated transcription factors and control …
proliferator-activated receptors (PPARs) are ligand-activated transcription factors and control …
An insight to treat cardiovascular diseases through phytochemicals targeting PPAR-α
S Sharma, D Sharma, M Dhobi, D Wang… - Molecular and Cellular …, 2024 - Springer
Peroxisome proliferator-activated receptor-α (PPAR-α) belonging to the nuclear hormone
receptor superfamily is a promising target for CVDs which mechanistically improves the …
receptor superfamily is a promising target for CVDs which mechanistically improves the …
Targeting PPARs for therapy of atherosclerosis: A review
M Miao, X Wang, T Liu, YJ Li, WQ Yu, TM Yang… - International journal of …, 2023 - Elsevier
Atherosclerosis, a chief pathogenic factor of cardiovascular disease, is associated with many
factors including inflammation, dyslipidemia, and oxidative stress. Peroxisome proliferator …
factors including inflammation, dyslipidemia, and oxidative stress. Peroxisome proliferator …
Pharmacological utility of PPAR modulation for angiogenesis in cardiovascular disease
N Wagner, KD Wagner - International Journal of Molecular Sciences, 2023 - mdpi.com
Peroxisome proliferator activated receptors, including PPARα, PPARβ/δ, and PPARγ, are
ligand-activated transcription factors belonging to the nuclear receptor superfamily. They …
ligand-activated transcription factors belonging to the nuclear receptor superfamily. They …
[HTML][HTML] PPARs in atherosclerosis: The spatial and temporal features from mechanism to druggable targets
Y Zheng, M Shao, Y Zheng, W Sun, S Qin, Z Sun… - Journal of Advanced …, 2024 - Elsevier
Background Atherosclerosis is a chronic and complex disease caused by lipid disorder,
inflammation, and other factors. It is closely related to cardiovascular diseases, the chief …
inflammation, and other factors. It is closely related to cardiovascular diseases, the chief …
PPARs and the cardiovascular system
M Hamblin, L Chang, Y Fan, J Zhang… - Antioxidants & redox …, 2009 - liebertpub.com
Peroxisome proliferator-activated receptors (PPARs) belong to the nuclear hormone-
receptor superfamily. Originally cloned in 1990, PPARs were found to be mediators of …
receptor superfamily. Originally cloned in 1990, PPARs were found to be mediators of …
The role of PPARs in atherosclerosis
C Duval, G Chinetti, F Trottein, JC Fruchart… - Trends in molecular …, 2002 - cell.com
Peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors
that regulate lipid and lipoprotein metabolism, glucose homeostasis and inflammation. The …
that regulate lipid and lipoprotein metabolism, glucose homeostasis and inflammation. The …
Peroxisome Proliferator-Activated Receptor??(PPAR??) and Atherosclerosis
I Gouni-Berthold, W Krone - Current Drug Targets …, 2005 - ingentaconnect.com
The peroxisome proliferator-activated receptors (PPARs) α, β/δ and γ are ligand-activated
transcription factors belonging to the nuclear receptor superfamily. PPARs heterodimerize …
transcription factors belonging to the nuclear receptor superfamily. PPARs heterodimerize …
PPAR agonists, atherogenic dyslipidemia and cardiovascular risk
D Nikolic, G Castellino, M Banach… - Current …, 2017 - ingentaconnect.com
Peroxisome proliferator-activated receptors (PPAR) are implicated in the pathology of
several metabolic diseases including obesity, diabetes, and atherosclerosis. PPAR agonists …
several metabolic diseases including obesity, diabetes, and atherosclerosis. PPAR agonists …
PPARγ in Atherosclerotic Endothelial Dysfunction: Regulatory Compounds and PTMs
J Luan, X Ji, L Liu - International Journal of Molecular Sciences, 2023 - mdpi.com
The formation of atherosclerotic plaques is one of the main sources of cardiovascular
disease. In addition to known risk factors such as dyslipidemia, diabetes, obesity, and …
disease. In addition to known risk factors such as dyslipidemia, diabetes, obesity, and …
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