[HTML][HTML] Verteporfin-loaded mesoporous silica nanoparticles inhibit mouse melanoma proliferation in vitro and in vivo

N Clemente, I Miletto, E Gianotti, M Invernizzi… - … of Photochemistry and …, 2019 - Elsevier
Melanoma is one of the most lethal tumors among the skin cancers, arising from complex
genetic mutations in melanocyte. Melanoma microenvironment is very heterogeneous …

[HTML][HTML] Verteporfin based silica nanoparticle for in vitro selective inhibition of human highly invasive melanoma cell proliferation

M Rizzi, S Tonello, BM Estevão, E Gianotti… - … of Photochemistry and …, 2017 - Elsevier
Photodinamic therapy (PDT) has gained an increasing interest as a new tool to treat skin
cancers such as melanoma. This clinical approach take advantage from the combination of …

[HTML][HTML] Verteporfin-Loaded Mesoporous Silica Nanoparticles' Topical Applications Inhibit Mouse Melanoma Lymphangiogenesis and Micrometastasis In Vivo

N Clemente, I Miletto, E Gianotti, M Sabbatini… - International Journal of …, 2021 - mdpi.com
Photodynamic therapy (PDT) has been pointed out as a candidate for improving melanoma
treatment. Nanotechnology application in PDT has increased its efficacy by reducing side …

[HTML][HTML] Encapsulation and enhanced release of resveratrol from mesoporous silica nanoparticles for melanoma therapy

D Marinheiro, BJML Ferreira, P Oskoei, H Oliveira… - Materials, 2021 - mdpi.com
Chemotherapy has limited success in the treatment of malignant melanoma due to fast
development of drug resistance and the low bioavailability of chemotherapeutic drugs …

Microneedle-assisted topical delivery of photodynamically active mesoporous formulation for combination therapy of deep-seated melanoma

HP Tham, K Xu, WQ Lim, H Chen, M Zheng… - ACS …, 2018 - ACS Publications
Topical treatment using photodynamic therapy (PDT) for many types of skin cancers has
largely been limited by the inability of existing photosensitizers to penetrate into the deep …

[HTML][HTML] Mesoporous silica-based nanoplatforms for the delivery of photodynamic therapy agents

S Hong, Y Choi - Journal of pharmaceutical investigation, 2018 - Springer
Photodynamic therapy (PDT) is an established method for the treatment of cancer which
utilizes light, a photosensitizer (PS), and oxygen. Unfavourable characteristics of most PSs …

Ru (II) polypyridine complex-functionalized mesoporous silica nanoparticles as photosensitizers for cancer targeted photodynamic therapy

J Karges, D Díaz-García, S Prashar… - ACS Applied Bio …, 2021 - ACS Publications
Cancer is the leading cause of death in the developed world. In the last few decades,
photodynamic therapy (PDT) has augmented the number of medical techniques to treat this …

Photosensitizer‐Mesoporous Silica Nanoparticles Combination for Enhanced Photodynamic Therapy

R Prieto‐Montero, T Arbeloa… - Photochemistry and …, 2023 - Wiley Online Library
Mesoporous silica nanoparticles (MSNs) are widely known for their versatile applications.
One of the most extended is as drug delivery systems for the treatment of cancer and other …

[HTML][HTML] Photodynamic therapeutic effect of nanostructured metal sulfide photosensitizers on cancer treatment

D Diaz-Diestra, HM Gholipour, M Bazian… - Nanoscale research …, 2022 - Springer
Photodynamic therapy (PDT) utilizes photosensitizers (PSs) to produce reactive oxygen
species (ROSs) upon irradiation, which causes the shutdown of vessels and deprives the …

[HTML][HTML] Photosensitizers-loaded Nanocarriers for enhancement of photodynamic therapy in melanoma treatment

AM Udrea, A Smarandache, A Dinache, C Mares… - Pharmaceutics, 2023 - mdpi.com
Malignant melanoma poses a significant global health burden. It is the most aggressive and
lethal form of skin cancer, attributed to various risk factors such as UV radiation exposure …