[HTML][HTML] Fungal CNS infections in Africa: the neuroimmunology of cryptococcal meningitis

SH Mohamed, TK Nyazika, K Ssebambulidde… - Frontiers in …, 2022 - frontiersin.org
Cryptococcal meningitis (CM) is the leading cause of central nervous system (CNS) fungal
infections in humans, with the majority of cases reported from the African continent. This is …

Cryptococcal meningitis

JN Day - Practical Neurology, 2004 - pn.bmj.com
INTRODUCTION The HIV pandemic has raised the profile of Cryptococcus neoformans from
an obscure yeast to the most important fungal cause of morbidity and death worldwide …

[HTML][HTML] Diagnosis and management of central nervous system cryptococcal infections in HIV-infected adults

C Skipper, M Abassi, DR Boulware - Journal of Fungi, 2019 - mdpi.com
Cryptococcal meningitis persists as a significant source of morbidity and mortality in persons
with HIV/AIDS, particularly in sub-Saharan Africa. Despite increasing access to …

[HTML][HTML] Immune correlates of HIV-associated cryptococcal meningitis

MW Tenforde, JE Scriven, TS Harrison… - PLoS …, 2017 - journals.plos.org
Cryptococcal meningitis (CM) is the leading cause of meningitis in much of sub-Saharan
Africa, where it causes up to 20% of all deaths in human immunodeficiency virus (HIV) …

[HTML][HTML] New insights into HIV/AIDS-associated cryptococcosis

S Antinori - International Scholarly Research Notices, 2013 - hindawi.com
Cryptococcal meningitis is a life-threatening opportunistic fungal infection in both HIV-
infected and HIV-uninfected patients. According to the most recent taxonomy, the …

Landmark clinical observations and immunopathogenesis pathways linked to HIV and Cryptococcus fatal central nervous system co‐infection

S Okurut, DR Boulware, J Olobo, DB Meya - Mycoses, 2020 - Wiley Online Library
Cryptococcal meningitis remains one of the leading causes of death among HIV‐infected
adults in the fourth decade of HIV era in sub‐Saharan Africa, contributing to 10%–20% of …

[HTML][HTML] Epidemiological characteristics of cryptococcal meningoencephalitis associated with Cryptococcus neoformans var. grubii from HIV-infected patients in …

RA Rakotoarivelo, M Raberahona… - PLoS Neglected …, 2020 - journals.plos.org
Cryptococcal meningoencephalitis (CM) remains the most prevalent invasive fungal
infection worldwide. The main objective of this study was to describe the prevalence of CM …

[HTML][HTML] Neuro-immune mechanisms of anti-cryptococcal protection

RA Drummond - Journal of Fungi, 2017 - mdpi.com
Cryptococcal meningitis (CM) is a life-threatening fungal disease affecting both
immunosuppressed and immunocompetent people. The main causative agent of CM is …

Cryptococcal meningitis: epidemiology, immunology, diagnosis and therapy

PR Williamson, JN Jarvis, AA Panackal… - Nature Reviews …, 2017 - nature.com
HIV-associated cryptococcal meningitis is by far the most common cause of adult meningitis
in many areas of the world that have high HIV seroprevalence. In most areas in Sub …

CD4+ T Cells Orchestrate Lethal Immune Pathology despite Fungal Clearance during Cryptococcus neoformans Meningoencephalitis

LM Neal, E Xing, J Xu, JL Kolbe, JJ Osterholzer… - MBio, 2017 - Am Soc Microbiol
Cryptococcus neoformans is a major fungal pathogen that disseminates to the central
nervous system (CNS) to cause fatal meningoencephalitis, but little is known about immune …