Antibiofilm activity of host defence peptides: complexity provides opportunities
Host defence peptides (HDPs) are integral components of innate immunity across all living
organisms. These peptides can exert direct antibacterial effects, targeting planktonic cells …
organisms. These peptides can exert direct antibacterial effects, targeting planktonic cells …
[HTML][HTML] Synthetic antibiofilm peptides
C De La Fuente-Núñez, MH Cardoso… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Bacteria predominantly exist as multicellular aggregates known as biofilms that are
associated with at least two thirds of all infections and exhibit increased adaptive resistance …
associated with at least two thirds of all infections and exhibit increased adaptive resistance …
Host defense (antimicrobial) peptides
E Sun, CR Belanger, EF Haney… - Peptide applications in …, 2018 - Elsevier
Small cationic, amphipathic peptides with critical roles in host defenses often exhibit
overlapping but distinct immunomodulatory activity, direct antimicrobial activity towards …
overlapping but distinct immunomodulatory activity, direct antimicrobial activity towards …
[HTML][HTML] Strategies in translating the therapeutic potentials of host defense peptides
The golden era of antibiotics, heralded by the discovery of penicillin, has long been
challenged by the emergence of antimicrobial resistance (AMR). Host defense peptides …
challenged by the emergence of antimicrobial resistance (AMR). Host defense peptides …
Antimicrobial host defence peptides: immunomodulatory functions and translational prospects
AM van der Does, PS Hiemstra… - … Peptides: Basics for …, 2019 - Springer
Cationic host defence peptides (CHDPs), also known as antimicrobial peptides, exhibit a
wide range of activities contributing to immune responses and resolution of infections …
wide range of activities contributing to immune responses and resolution of infections …
[HTML][HTML] Antibiofilm peptides: overcoming biofilm-related treatment failure
Health leaders and scientists worldwide consider antibiotic resistance among the world's
most dangerous pathogens as one of the biggest threats to global health. Antibiotic …
most dangerous pathogens as one of the biggest threats to global health. Antibiotic …
Antimicrobial host defence peptides: functions and clinical potential
Cationic host defence peptides (CHDP), also known as antimicrobial peptides, are naturally
occurring peptides that can combat infections through their direct microbicidal properties …
occurring peptides that can combat infections through their direct microbicidal properties …
Multifunctional cationic host defence peptides and their clinical applications
ATY Yeung, SL Gellatly, REW Hancock - Cellular and Molecular Life …, 2011 - Springer
With the rapid rise in the emergence of bacterial strains resistant to multiple classes of
antimicrobial agents, there is an urgent need to develop novel antimicrobial therapies to …
antimicrobial agents, there is an urgent need to develop novel antimicrobial therapies to …
[HTML][HTML] Antimicrobial and antibiofilm peptides
A Di Somma, A Moretta, C Canè, A Cirillo, A Duilio - Biomolecules, 2020 - mdpi.com
The increasing onset of multidrug-resistant bacteria has propelled microbiology research
towards antimicrobial peptides as new possible antibiotics from natural sources …
towards antimicrobial peptides as new possible antibiotics from natural sources …
Perspectives for clinical use of engineered human host defense antimicrobial peptides
Infectious diseases caused by bacteria, viruses or fungi are among the leading causes of
death worldwide. The emergence of drug-resistance mechanisms, especially among …
death worldwide. The emergence of drug-resistance mechanisms, especially among …