Multifunctional host defense peptides: antimicrobial peptides, the small yet big players in innate and adaptive immunity

C Auvynet, Y Rosenstein - The FEBS journal, 2009 - Wiley Online Library
The term 'antimicrobial peptides' refers to a large number of peptides first characterized on
the basis of their antibiotic and antifungal activities. In addition to their role as endogenous …

Antimicrobial peptides important in innate immunity

A Cederlund, GH Gudmundsson… - The FEBS …, 2011 - Wiley Online Library
Antimicrobial peptides are present in all walks of life, from plants to animals, and they are
considered to be endogenous antibiotics. In general, antimicrobial peptides are …

[HTML][HTML] Recent advances in the field of antimicrobial peptides in inflammatory diseases

P Méndez-Samperio - Advanced biomedical research, 2013 - journals.lww.com
Antimicrobial peptides are cationic molecules, which participate in multiple aspects of the
immune response including the control of inflammatory diseases, characteristic that make …

Biology and clinical relevance of naturally occurring antimicrobial peptides

RL Gallo, M Murakami, T Ohtake, M Zaiou - Journal of Allergy and Clinical …, 2002 - Elsevier
Within the last decade, several peptides have been discovered on the basis of their ability to
inhibit the growth of potential microbial pathogens. These so-called antimicrobial peptides …

Antimicrobial peptides: general overview and clinical implications in human health and disease

E Guaní-Guerra, T Santos-Mendoza, SO Lugo-Reyes… - Clinical …, 2010 - Elsevier
Antimicrobial peptides (AMPs) are evolutionarily conserved molecules involved in the
defense mechanisms of a wide range of organisms. Produced in bacteria, insects, plants …

Endogenous production of antimicrobial peptides in innate immunity and human disease

RL Gallo, V Nizet - Current allergy and asthma reports, 2003 - Springer
Antimicrobial peptides are diverse and evolutionarily ancient molecules produced by all
living organisms. Peptides belonging to the cathelicidin and defensin gene families exhibit …

[HTML][HTML] Antimicrobial peptides in innate immunity against mycobacteria

DM Shin, EK Jo - Immune Network, 2011 - synapse.koreamed.org
Antimicrobial peptides/proteins are ancient and naturallyoccurring antibiotics in innate
immune responses in a variety of organisms. Additionally, these peptides have been …

Leukocyte antimicrobial peptides: multifunctional effector molecules of innate immunity

A Risso - Journal of leukocyte biology, 2000 - academic.oup.com
Antimicrobial peptides are effector molecules of innate immunity that provide a first line of
defense against pathogens. In mammals, they are stored in granules of leukocytes and are …

Antimicrobial peptides: an essential component of the skin defensive barrier

MH Braff, RL Gallo - Antimicrobial Peptides and Human Disease, 2006 - Springer
The skin is positioned at the interface between an organism's internal milieu and an external
environment characterized by constant assault with potential microbial pathogens. While the …

Human defensins and cathelicidins in the skin: beyond direct antimicrobial properties

F Niyonsaba, I Nagaoka… - Critical Reviews™ in …, 2006 - dl.begellhouse.com
ABSTRACT A cutaneous barrier defends the body against invading pathogenic
microorganisms due to both innate and adaptive immunity. The innate immune system …