Aim Our aim was to determine the effectiveness and safety of a procalcitonin‐guided
protocol to decrease antibiotic use in infants with severe bronchiolitis. Methods This …

Abstract Background Acute respiratory infections (ARIs) comprise a large and
heterogeneous group of infections including bacterial, viral and other aetiologies. In recent …

Background Antibiotics are overused in children and adolescents with lower respiratory tract
infection (LRTI). Serum-procalcitonin (PCT) can be used to guide treatment when bacterial …

Objective: To establish the efficacy of an algorithm based on the biomarker procalcitonin
(PCT) to reduce antibiotic exposure in pediatric patients with lower respiratory tract infection …

In order to evaluate the use of an algorithm based on a procalcitonin (PCT) cut-off value as a
means of guiding antibiotic therapy, 319 hospitalised children with uncomplicated …

BACKGROUND The utility of procalcitonin to manage patients with infections is unclear. A
systematic review of comparative studies using procalcitonin‐guided antibiotic therapy in …

The objective was to evaluate the use of procalcitonin (PCT) and C-reactive protein (CRP)
for the diagnosis of bacterial infection in bronchiolitis patients. A prospective, single-centre …

Objective The aim of this study was to conduct a preliminary analysis of serum procalcitonin
(PCT) to predict bacterial coinfection in infants with acute bronchiolitis. Methods …

Background Knowledge of key drivers for antibiotic prescribing in pediatric lower respiratory
tract infection (LRTI) could support rational antibiotic use. Thus, we aimed to determine the …

Background: The utility of procalcitonin testing in the pediatric intensive care unit (PICU) is
not known. We sought to determine the impact of a procalcitonin-guided antibiotic treatment …