Antitumor effects of polysorbate-80 coated gemcitabine polybutylcyanoacrylate nanoparticles in vitro and its pharmacodynamics in vivo on C6 glioma cells of a brain …
CX Wang, LS Huang, LB Hou, L Jiang, ZT Yan… - Brain research, 2009 - Elsevier
Polybutylcyanoacrylate (PBCA) nanoparticles coated with polysorbate-80 have been
extensively studied for delivery of drugs into the animal models; however, 1% polysorbate …
extensively studied for delivery of drugs into the animal models; however, 1% polysorbate …
Efficacy of Cisplatin-loaded polybutyl cyanoacrylate nanoparticles on the glioblastoma
H Ebrahimi Shahmabadi, F Movahedi… - Tumor Biology, 2014 - Springer
Glioblastoma is known as one of the most aggressive human cancers. To gain access of the
brain, therapeutic agents must overcome blood–brain barrier (BBB). In this study, Cisplatin …
brain, therapeutic agents must overcome blood–brain barrier (BBB). In this study, Cisplatin …
Enhanced brain targeting of temozolomide in polysorbate-80 coated polybutylcyanoacrylate nanoparticles
XH Tian, XN Lin, F Wei, W Feng, ZC Huang… - International journal …, 2011 - Taylor & Francis
Background Polybutylcyanoacrylate (PBCA) nanoparticles coated with polysorbate-80 have
been extensively proposed for delivering drugs into the animal brain and have shown great …
been extensively proposed for delivering drugs into the animal brain and have shown great …
Influence of surfactants, polymer and doxorubicin loading on the anti-tumour effect of poly (butyl cyanoacrylate) nanoparticles in a rat glioma model
A Ambruosi, S Gelperina, A Khalansky… - Journal of …, 2006 - Taylor & Francis
Poly (n-butyl cyanoacrylate) nanoparticles coated with polysorbate-80 can enable the
transport of bound drugs across the blood–brain barrier (BBB) after iv injection. In the …
transport of bound drugs across the blood–brain barrier (BBB) after iv injection. In the …
Body distribution of polysorbate‐80 and doxorubicin-loaded [14C]poly(butyl cyanoacrylate) nanoparticles after iv administration in rats
A Ambruosi, H Yamamoto, J Kreuter - Journal of drug targeting, 2005 - Taylor & Francis
Previously it was shown that poly (butyl cyanoacrylate)(PBCA) nanoparticles coated with
polysorbate 80 are able to cross the blood-brain barrier (BBB) after iv administration. The …
polysorbate 80 are able to cross the blood-brain barrier (BBB) after iv administration. The …
Biodistribution of polysorbate 80-coated doxorubicin-loaded [14C]-poly(butyl cyanoacrylate) nanoparticles after intravenous administration to glioblastoma-bearing …
A Ambruosi, AS Khalansky, H Yamamoto… - Journal of drug …, 2006 - Taylor & Francis
It was recently shown that doxorubicin (DOX) bound to polysorbate-coated nanoparticles
(NP) crossed the intact blood–brain barrier (BBB), and thus reached therapeutic …
(NP) crossed the intact blood–brain barrier (BBB), and thus reached therapeutic …
Treatment of glioblastoma with poly (isohexyl cyanoacrylate) nanoparticles
S Wohlfart, AS Khalansky, C Bernreuther… - International journal of …, 2011 - Elsevier
Glioblastomas belong to the most devastating cancer diseases. For this reason, polysorbate
80 (Tween 80®)-coated poly (isohexyl cyanoacrylate)(PIHCA)(Monorex®) nanoparticles …
80 (Tween 80®)-coated poly (isohexyl cyanoacrylate)(PIHCA)(Monorex®) nanoparticles …
Hyaluronic acid coated poly (butyl cyanoacrylate) nanoparticles as anticancer drug carriers
M He, Z Zhao, L Yin, C Tang, C Yin - International journal of pharmaceutics, 2009 - Elsevier
The hyaluronic acid (HA) coated poly (butyl cyanoacrylate)(PBCA) nanoparticles were
synthesized through radical polymerization of butyl cyanoarylate (BCA) initiated by cerium …
synthesized through radical polymerization of butyl cyanoarylate (BCA) initiated by cerium …
Toxicological studies of doxorubicin bound to polysorbate 80-coated poly (butyl cyanoacrylate) nanoparticles in healthy rats and rats with intracranial glioblastoma
SE Gelperina, AS Khalansky, IN Skidan, ZS Smirnova… - Toxicology letters, 2002 - Elsevier
Polysorbate 80-coated poly (butyl cyanoacrylate) nanoparticles (NP) were shown to enable
the transport of a number of drugs including the anti-tumour antibiotic doxorubicin (DOX) …
the transport of a number of drugs including the anti-tumour antibiotic doxorubicin (DOX) …
Cytotoxicity of doxorubicin bound to poly (butyl cyanoacrylate) nanoparticles in rat glioma cell lines using different assays
B Sanchez De Juan, H Von Briesen… - Journal of drug …, 2006 - Taylor & Francis
The cytotoxicity of doxorubicin bound to poly (butyl cyanoacrylate) nanoparticles (Dox-PBCA-
NP) was investigated in the rat glioma cell lines GS-9L, F-98 and RG-2. MTT and LDH …
NP) was investigated in the rat glioma cell lines GS-9L, F-98 and RG-2. MTT and LDH …