This chapter will provide an up-to-date depiction of the molecular networks involved in the
osteogenic process, focusing on main genes and signaling pathways (schematically …

Bone tissue represents a specialized connective tissue, comprising metabolically active
cells within a mineralized extracellular matrix, that are vital to the performance of its …

One of the key issues in studying organogenesis is to understand the mechanisms
underlying the differentiation of progenitor cells into more specialized cells of individual …

This book provides an in-depth overview of current knowledge about Osteogenesis,
including molecular mechanisms, transcriptional regulators, scaffolds, cell biology …

Bone is a dynamic tissue in constant change; maintenance of bone mass throughout life
relies on the bone remodeling process, which continually replaces old and damaged bone …

The skeleton, like every organ, has specific developmental and functional characteristics
that define its identity in biologic and pathologic terms. Skeleton is composed of multiple …

Osteoporosis is a complex multifactorial disorder of the skeleton. Genetic factors are
important in determining peak bone mass and structure, as well as the predisposition to …

Bone is not an inert structure but a living and metabolic active tissue, which undergoes
continuous remodeling throughout life, to allow bone architecture to respond to mechanical …

Bone is a highly specialized form of connective tissue present in most vertebrate animals as
part of the endoskeleton. Structurally speaking, bone is mainly constituted by an organic …

Publisher Summary This chapter presents the cell biology of osteoblasts within the content
of current understanding of the regulatory controls operative in promoting osteoblast …