Effect of SARS-CoV-2 proteins on vascular permeability

R Rauti, M Shahoha, Y Leichtmann-Bardoogo… - Elife, 2021 - elifesciences.org
Severe acute respiratory syndrome (SARS)-CoV-2 infection leads to severe disease
associated with cytokine storm, vascular dysfunction, coagulation, and progressive lung …

Effect of SARS-CoV-2 proteins on vascular permeability

R Rossana, S Meishar, LB Yael, N Rami, P Eyal… - eLife, 2021 - search.proquest.com
Severe acute respiratory syndrome (SARS)-CoV-2 infection leads to severe disease
associated with cytokine storm, vascular dysfunction, coagulation, and progressive lung …

Gene expression profiling of SARS-CoV-2 infections reveal distinct primary lung cell and systemic immune infection responses that identify pathways relevant in …

MA Moni, JMW Quinn, N Sinmaz… - Briefings in …, 2021 - academic.oup.com
To identify key gene expression pathways altered with infection of the novel coronavirus
SARS-CoV-2, we performed the largest comparative genomic and transcriptomic analysis to …

[HTML][HTML] CovidExpress: an interactive portal for intuitive investigation on SARS-CoV-2 related transcriptomes

MN Djekidel, W Rosikiewicz, JC Peng, TD Kanneganti… - bioRxiv, 2021 - ncbi.nlm.nih.gov
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in humans
could cause coronavirus disease 2019 (COVID-19). Since its first discovery in Dec 2019 …

[HTML][HTML] Dysregulated transcriptional responses to SARS-CoV-2 in the periphery support novel diagnostic approaches

MT McClain, FJ Constantine, R Henao, Y Liu, EL Tsalik… - medRxiv, 2020 - ncbi.nlm.nih.gov
In order to elucidate novel aspects of the host response to SARS-CoV-2 we performed RNA
sequencing on peripheral blood samples across 77 timepoints from 46 subjects with COVID …

Identification of COVID-19-relevant transcriptional regulatory networks and associated kinases as potential therapeutic targets

C Su, S Rousseau, A Emad - bioRxiv, 2020 - biorxiv.org
Identification of transcriptional regulatory mechanisms and signaling networks involved in
the response of host to infection by SARS-CoV-2 is a powerful approach that provides a …

Inferring SARS-CoV-2 functional genomics from viral transcriptome with identification of potential antiviral drugs and therapeutic targets

X Pan, X Li, S Ning, H Zhi - Cell & Bioscience, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is an emerging infectious disease caused
by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and has posed a …

Molecular signatures in the progression of COVID-19 severity

R De, RK Azad - Scientific Reports, 2022 - nature.com
SARS-CoV-2 is the causative agent of COVID-19 that has infected over 642 million and
killed over 6.6 million people around the globe. Underlying a wide range of clinical …

[图书][B] Genomic, Immunologic, Transcriptional and Functional Interrogation of SARS-CoV-2 and Respiratory Syncytial Virus

S Sunshine - 2022 - search.proquest.com
SARS-CoV-2 and RSV are ubiquitous respiratory viruses, and a leading cause of morbidity
and mortality globally. Despite great advances in our biological understanding of these …

[PDF][PDF] Transcriptomic analysis of sorted lung cells revealed a proviral activity of the NF-κB pathway toward SARS-CoV-2

A Bhargava, U Szachnowski, M Chazal, D Foretek… - Iscience, 2023 - cell.com
Investigations of cellular responses to viral infection are commonly performed on mixed
populations of infected and uninfected cells or using single-cell RNA sequencing, leading to …