Genome-wide identification of methylated CpG sites in nongenital cutaneous warts

LN Al-Eitan, MA Alghamdi, AH Tarkhan… - BMC Medical …, 2020 - Springer
Background Low-risk HPV infection has not been the subject of epigenetic investigation. The
present study was carried out in order to investigate the methylation status of CpG sites in …

Genome-wide CpG island methylation profiles of cutaneous skin with and without HPV infection

LN Al-Eitan, MA Alghamdi, AH Tarkhan… - International Journal of …, 2019 - mdpi.com
HPV infection is one of the most commonly transmitted diseases among the global
population. While it can be asymptomatic, non-genital HPV infection often gives rise to …

[HTML][HTML] Epigenome-wide analysis of common warts reveals aberrant promoter methylation

LN Al-Eitan, MA Alghamdi, AH Tarkhan… - … Journal of Medical …, 2020 - ncbi.nlm.nih.gov
Epigenetic alteration of host DNA is a common occurrence in both low-and high-risk human
papillomavirus (HPV) infection. Although changes in promoter methylation have been widely …

Genome-wide tiling array analysis of HPV-induced warts reveals aberrant methylation of protein-coding and non-coding regions

LN Al-Eitan, MA Alghamdi, AH Tarkhan, FA Al-Qarqaz - Genes, 2019 - mdpi.com
The human papillomaviruses (HPV) are a group of double-stranded DNA viruses that exhibit
an exclusive tropism for squamous epithelia. HPV can either be low-or high-risk depending …

[HTML][HTML] Global gene methylation profiling of common warts caused by human papillomaviruses infection

MA Alghamdi, LN Al-Eitan, AH Tarkhan… - Saudi Journal of …, 2021 - Elsevier
Infection with the human papillomaviruses (HPV) often involves the epigenetic modification
of the host genome. Despite its prevalence among the population, host genome methylation …

Integrative analysis of gene expression and DNA methylation to identify biomarkers of non-genital warts induced by low-risk human papillomaviruses infection

MA Alghamdi, LN Al-Eitan, AH Tarkhan - Heliyon, 2023 - cell.com
Background Human papillomaviruses have been shown to dysregulate the gene expression
and DNA methylation profiles of their host cells over the course of infection. However, there …

Analysis of CpG methylation sites and CGI among human papillomavirus DNA genomes

SC Galván, M Martínez-Salazar, VM Galván, R Méndez… - BMC genomics, 2011 - Springer
Abstract Background The Human Papillomavirus (HPV) genome is divided into early and
late coding sequences, including 8 open reading frames (ORFs) and a regulatory region …

Characterization of HPV DNA methylation of contiguous CpG sites by bisulfite treatment and massively parallel sequencing—the FRAGMENT approach

C Sun, T McAndrew, BC Smith, Z Chen, M Frimer… - Frontiers in …, 2014 - frontiersin.org
Invasive cervix cancer (ICC) is the third most common malignant tumor in women and
human papillomavirus 16 (HPV16) causes more than 50% of ICC. DNA methylation is a …

Unique DNA methylation signature in HPV-positive head and neck squamous cell carcinomas

D Degli Esposti, A Sklias, SC Lima… - Genome medicine, 2017 - Springer
Background Head and neck squamous cell carcinomas (HNSCCs) represent a
heterogeneous group of cancers for which human papilloma virus (HPV) infection is an …

Impact of host methylome on cervical cancer pathogenesis

S Sen, S Bhattacharjee, I Mukhopadhyay, P Mandal… - Cancer Research, 2015 - AACR
Identification of episomal HPV16 in cervical cancers (CaCx) besides the integrated forms,
prompted us to investigate the global CpG methylation signatures among the different …