Comparative Proteomics Analysis of Human Macrophages Infected with Virulent Mycobacterium bovis

P Li, R Wang, W Dong, L Hu, B Zong… - Frontiers in cellular …, 2017 - frontiersin.org
Mycobacterium bovis (M. bovis), the most common pathogens of tuberculosis (TB), is virulent
to human and cattle, and transmission between cattle and humans warrants reconsideration …

Exploring optimal drug targets through subtractive proteomics analysis and pangenomic insights for tailored drug design in tuberculosis

MF Khan, A Ali, HM Rehman, S Noor Khan… - Scientific Reports, 2024 - nature.com
Tuberculosis (TB), caused by Mycobacterium tuberculosis, ranks among the top causes of
global human mortality, as reported by the World Health Organization's 2022 TB report. The …

Revealing Corynebacterium glutamicum proteoforms through top-down proteomics

RM Melo, JMF de Souza, TCR Williams, W Fontes… - Scientific Reports, 2023 - nature.com
Corynebacterium glutamicum is a bacterium widely employed in the industrial production of
amino acids as well as a broad range of other biotechnological products. The present study …

Genome-wide core proteome analysis of Brucella melitensis strains for potential drug target prediction

N Rahman, M Shah, I Muhammad… - Mini Reviews in …, 2021 - ingentaconnect.com
Introduction: Brucella melitensis is a facultative intracellular bacterial pathogen that causes
abortion in goats and sheep and Malta fever in humans. In humans, chronic infection occurs …

In silico approach to identify microsatellite candidate biomarkers to differentiate the biovar of Corynebacterium pseudotuberculosis genomes

KC Pinheiro, BVA Gois, WG Nogueira… - Frontiers in …, 2022 - frontiersin.org
Corynebacterium pseudotuberculosis is the causative bacterial agent of the zoonotic
disease known as caseous lymphadenitis, and it presents several mechanisms of response …

Differential Exoproteome Analysis of Two Corynebacterium pseudotuberculosis Biovar Ovis Strains Isolated from Goat (1002) and Sheep (C231)

WM Silva, N Seyffert, A Ciprandi, AV Santos… - Current …, 2013 - Springer
Corynebacterium pseudotuberculosis is the etiologic agent of caseous lymphadenitis a
chronic infectious disease affecting small ruminants. The 2D-DIGE technique was used to …

Structural proteomics and computational analysis of a deadly pathogen: combating Mycobacterium tuberculosis from multiple fronts

M Strong, CW Goulding - Methods of Biochemical Analysis, 2006 - books.google.com
Tuberculosis (TB) is a devastating respiratory disease caused by the bacterium
Mycobacterium tuberculosis. This disease of the lungs has been estimated to result in two …

The Corynebacterium pseudotuberculosis in silico predicted pan-exoproteome

AR Santos, A Carneiro, A Gala-García, A Pinto, D Barh… - BMC genomics, 2012 - Springer
Background Pan-genomic studies aim, for instance, at defining the core, dispensable and
unique genes within a species. A pan-genomics study for vaccine design tries to assess the …

Weighted gene co-expression network analysis identifies key modules and hub genes associated with mycobacterial infection of human macrophages

L Lu, RL Wei, S Bhakta, SJ Waddell, E Boix - Antibiotics, 2021 - mdpi.com
Tuberculosis (TB) is still a leading cause of death worldwide. Treatments remain
unsatisfactory due to an incomplete understanding of the underlying host–pathogen …

Mapping and comprehensive analysis of the extracellular and cell surface proteome of the human pathogen Corynebacterium diphtheriae

N Hansmeier, TC Chao, J Kalinowski, A Pühler… - …, 2006 - Wiley Online Library
Secreted proteins of the human pathogen Corynebacterium diphtheriae might be involved in
important pathogen–host cell interactions. Here, we present the first systematic reference …