A multiomic approach to defining the essential genome of the globally important pathogen Corynebacterium diphtheriae

ECA Goodall, C Azevedo Antunes, J Möller… - PLoS …, 2023 - journals.plos.org
Diphtheria is a respiratory disease caused by Corynebacterium diphtheriae. While the toxin-
based vaccine has helped control outbreaks of the disease since the mid-20th century there …

A comprehensive proteomic analysis of Mycobacterium bovis bacillus Calmette–Guérin using high resolution Fourier transform mass spectrometry

J Zheng, L Liu, C Wei, W Leng, J Yang, W Li, J Wang… - Journal of …, 2012 - Elsevier
Since 1921, Mycobacterium bovis bacillus Calmette–Guérin (BCG) has been recognized as
an important vaccine to prevent tuberculosis worldwide. Nonetheless, a global analysis of …

Comparative analyses of nonpathogenic, opportunistic, and totally pathogenic mycobacteria reveal genomic and biochemical variabilities and highlight the survival …

SA Rahman, Y Singh, S Kohli, J Ahmad, NZ Ehtesham… - MBio, 2014 - Am Soc Microbiol
Mycobacterial evolution involves various processes, such as genome reduction, gene
cooption, and critical gene acquisition. Our comparative genome size analysis of 44 …

Mycobacterium tuberculosis proteome microarray for global studies of protein function and immunogenicity

J Deng, L Bi, L Zhou, S Guo, J Fleming, H Jiang… - Cell reports, 2014 - cell.com
Poor understanding of the basic biology of Mycobacterium tuberculosis (MTB), the
etiological agent of tuberculosis, hampers development of much-needed drugs, vaccines …

The genetic proteome: Using genetics to inform the proteome of mycobacterial pathogens

KR Nicholson, CB Mousseau, MM Champion… - PLoS …, 2021 - journals.plos.org
Mycobacterial pathogens pose a sustained threat to human health. There is a critical need
for new diagnostics, therapeutics, and vaccines targeting both tuberculous and …

In-depth systems biological evaluation of bovine alveolar macrophages suggests novel insights into molecular mechanisms underlying Mycobacterium bovis infection

A Hasankhani, A Bahrami, S Mackie… - Frontiers in …, 2022 - frontiersin.org
Objective Bovine tuberculosis (bTB) is a chronic respiratory infectious disease of domestic
livestock caused by intracellular Mycobacterium bovis infection, which causes~ $3 billion in …

Evolution and genomics of the Mycobacterium tuberculosis complex

AMS Guimaraes, AR Allen… - Frontiers in Microbiology, 2023 - frontiersin.org
The organisms that cause tuberculosis are responsible for debilitating, chronic disease
across a wide swathe of the human and non-human animal kingdoms, with multiple host …

Functional characterization of the Mycobacterium abscessus genome coupled with condition specific transcriptomics reveals conserved molecular strategies for host …

AA Miranda-CasoLuengo, PM Staunton, AM Dinan… - BMC genomics, 2016 - Springer
Background Mycobacterium abscessus subsp. abscessus (MAB) is a highly drug resistant
mycobacterium and the most common respiratory pathogen among the rapidly growing non …

MyxoPortal: a database of myxobacterial genomic features

RG Swetha, BS Arakal, S Rajendran, K Sekar… - Database, 2024 - academic.oup.com
Myxobacteria are predatory bacteria with antimicrobial activity, utilizing complex
mechanisms to kill their prey and assimilate their macromolecules. Having large genomes …

Evidence for Reductive Genome Evolution and Lateral Acquisition of Virulence Functions in Two Corynebacterium pseudotuberculosis Strains

JC Ruiz, V D'Afonseca, A Silva, A Ali, AC Pinto… - PloS one, 2011 - journals.plos.org
Background Corynebacterium pseudotuberculosi s, a Gram-positive, facultative intracellular
pathogen, is the etiologic agent of the disease known as caseous lymphadenitis (CL). CL …